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13 Contraindications to Radiation Therapy

Updated: November 2004

Radiation Therapy may be relatively or absolutely contraindicated in the following circumstances:

a)

Significant pre-existing lung disease particularly where the diffusing capacity is reduced

b)

Pre-existing pulmonary tuberculosis

c)

Cardiomyopathy

d)

Connective tissue disorders (S.L.E., scleroderma, etc.) with significant vasculitis. The use of radiation may not be contraindicated with all connective tissue disorders. Referral to a radiation oncologist is advised.

e)

Prior radiation therapy to the same part.



In such situations partial mastectomy may therefore be inappropriate in that the radiation therapy may be precluded. With current anesthetic techniques a formal modified radical mastectomy with a therapeutic axillary dissection is usually tolerable and the treatment of choice for these patients.