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3.4 Staging

Revised June 2011

1) Clinico pathologic Considerations

Gross Description

Gross description of the hysterectomy specimen should include:

a) in a polyp or not
b) Location of the tumour within the uterus
c) The depth of myometrial invasion (luminal or serosal half)
d) The presence or absence of cervical involvement

Microscopic Description

a)

The histologic type

b)

The histologic grade (1-3)

c)

Myometrial invasion if present

i) Luminal half

ii) Serosal half

d)

The presence or absence of lymphatic or vascular invasion and degree

e)

Perilymphatic inflammation (slight, moderate, marked)

f)

Cervical involvement (mucosal extension or stromal involvement)

g)

Lymph node involvement

h)

Adnexal involvement

i)

Cytology of peritoneal fluid



2) Staging Diagram

Corpus uteri.pdf  

3) Preoperative Investigations for Staging

  • chest x-ray
  • endocervical curretage
  • imaging with CT or U/S as appropriate
  • rarely some patients may need cystoscopy or sigmoidoscopy
  • tumor markers: CA 125, CA 19-9, CA 15-3, CEA