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4.4 Staging

 1) Classification Criteria(FIGO/UICC 1997)

TNM FIGO  
TX   Primary tumour cannot be assessed
T0   No evidence of primary tumour
TIS 0 Carcinoma in situ (preinvasive carcinoma)
T1 I Cervical carcinoma confined to uterus (extension to corpus should be disregarded)
T1a IA Invasive cancer identified only microscopically. All gross lesions even with superficial invasion are stage T1b/IB cancers.
T1a1 IA1 Stromal invasion no greater than 3.0 mm in depth and no wider than 7.0 mm
T1a2 IA2 Measured invasion of stroma greater than 3.0 mm and no greater than 5.0 mm with horizontal spread 7.0 mm or less
Note: The depth of invasion should not be more than 5 mm taken from the base of the epithelium, either surface or glandular, from which it originates. Vascular space involvement, either venous or lymphatic, should not alter the staging, but should be specifically recorded so as to determine whether it should affect treatment decisions in the future.
T1b IB Clinical lesions confined to the cervix or microscopic lesion greater than T1a2/IA2
T1b1 IB1 Clinical lesions not greater than 4.0 cm in size
T1b2 IB2 Clinical lesions greater than 4.0 cm in size
T2 II Tumour invades beyond uterus but not to pelvic wall or to lower third of the vagina
T2a IIA Without parametrial invasion
T2b IIB With parametrial invasion
T3 III Tumour extends to pelvic wall and/or involves lower third of vagina and/or causes hydronephrosis or non-functioning kidney
T3a IIIA Tumour involves lower third of vagina, no extension to pelvic wall
T3b IIIB Tumour extends to pelvic wall and/or causes hydronephrosis or non-functioning kidney
T4 IVA Tumour invades mucosa of bladder or rectum and/or extends beyond true pelvis
Note: the presence of bullous edema is not sufficient to classify a tumour as T4
M1 IVB Distant metastasis

2) Staging Diagram

Cervix Staging    Click image
for larger version

3) Investigations for Staging

Following biopsy confirmation of carcinoma of the cervix, history and physical examination and staging, the following lab and radiological studies should be done: 

  1. Lab studies: CBC, differential, platelet count, BUN and creatinine, liver function tests and
  2. Cystoscopy, sigmoidoscopy
  3. Radiological studies: Chest X-ray, CT scan of the abdomen and pelvis.

Referral, however, should not be delayed.


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Unofficial document if printed. Please refer to the following web address for up-to-date information: http://www.bccancer.bc.ca/HPI/CancerManagementGuidelines/Gynecology/UterineCervix1of2/4Staging.htm