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5.2 Staging
1) Classification Criteria (TNM Staging)
T Primary Tumour
| Tis |
Preinvasive carcinoma (carcinoma in situ) |
| T1 |
Lesions 2 cm or less in size confined to vulva or perineum. No nodal metastasis |
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T1a |
Lesions 2 cm or less in size confined to the vulva or perineum and with stromal invasion no greater than 1.0 mm.* No nodal metastasis |
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T1b |
Lesions 2 cm or less in size confined to the vulva or perineum and with stromal invasion greater than 1.0 mm. No nodal metastasis. |
| ** The depth of invasion is defined as the measurement of the tumor from the epithelial-stromal junction of the adjacent most superficial dermal papilla to the deepest point of invasion. |
| T2 |
Tumour confined to the vulva and/or perineum - >2 cm in greatest dimension |
| T3 |
Tumour of any size with adjacent spread to the urethra and/or vagina and/or to the anus |
| T4 |
Tumour of any size infiltrating the bladder mucosa and/or the rectal mucosa, including the upper part of the urethral mucosa and/or fixed to the bone |
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| N Regional Lymph Nodes |
| N0 |
No nodes palpable |
| N1 |
Unilateral regional lymph node metastasis |
| N2 |
Bilateral regional lymph node metastases |
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| M Distant Metastasis |
| M0 |
No clinical metastasis |
| M1 |
Distant metastasis (including pelvic lymph node metastasis) |
Clinical Stage Grouping (FIGO)
| Stage 0 |
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| Tis |
Carcinoma in situ; intraepithelial carcinoma |
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| Stage I |
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| T1 N0 M0 |
Tumour confined to the vulva and/or perineum - 2 cm or less in greatest dimension, nodes are not palpable |
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| Stage II |
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| T2 N0 M0 |
Tumour confined to the vulva and/or perineum - more than 2 cm in greatest dimension, nodes are not palpable |
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| Stage III |
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| T3 N0 M0 |
Tumour of any size with
1) adjacent spread to the lower urethra and/or the vagina, or the anus, and/or
2) unilateral regional lymph node metastasis |
| T3 N1 M0 |
| T1 N1 M0 |
| T2 N1 M0 |
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| Stage IVA |
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| T1 N2 M0 |
Tumour invades any of the following:
Upper urethra, bladder mucosa, rectal mucosa, pelvic bone, and/or bilateral regional node metastasis. |
| T2 N2 M0 |
| T3 N2 M0 |
| T4 Any N M0 |
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| Stage IVB |
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| Any T |
Any distant metastasis including pelvic lymph nodes |
| Any N, M1 |
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