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2. Predisposing Factors / Prevention
The association between asbestos (amphibole types) and mesothelioma is well established and a definite history of exposure is present in 60-70% of cases. Definite occupational exposure to asbestos in mines, mills, industry, mining, plumbing, insulating, and among shipyard workers should be documented for medicolegal and workman's compensation purposes. Clinicians considering the diagnosis of mesothelioma should take a detailed exposure history, emphasising the period between 20-50 years before diagnosis and including possible household contact exposure. Brief exposures may be long forgotten.
Since the early 1970's, legislation has decreased contamination of the environment by asbestos. The presence of asbestos fibres in the lungs of members of the general population suggests that exposure may occur unknowingly.
Reference:
- McDonald AD, McDonald JC. Epidemiology of malignant mesothelioma. In: Antman K, Aisner J, eds. Asbestos-related malignancy. Orlando: Grune & Stratton, 1987:31-55.
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