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Chemotherapy Protocols
	Breast

Breast

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The information contained in these documents is a statement of consensus of BC Cancer Agency professionals regarding their views of currently accepted approaches to treatment. Any clinician seeking to apply or consult these documents is expected to use independent medical judgement in the context of individual clinical circumstances to determine any patient's care or treatment. Use of these documents is at your own risk and is subject to BC Cancer Agency's terms of use, available at www.bccancer.bc.ca/legal.htm.

Please note: All links in the tables below open PDF documents

See Adjuvant treatments
See Locally Advanced treatments
See Advanced treatments

ADJUVANT TREATMENTS PROTOCOL CODE and DESCRIPTION	AVAILABLE DOCUMENTS (revision date indicated in red)
BRAJAC: Adjuvant therapy for breast cancer using Doxorubicin and Cyclophosphamide	- Protocol (27 Jun 2011) - Preprinted Order (27 Jun 2011) - Patient Handout (17 Jun 2005)
BRAJACT: Adjuvant Therapy for Breast Cancer using Doxorubicin and Cyclophosphamide followed by Paclitaxel	- Protocol (27 Jun 2011) - Preprinted Order (27 Jun 2011) - Patient Handout (10 Nov 2006)
BRAJACTG: Adjuvant Therapy for Breast Cancer using Dose Dense Therapy: Doxorubicin and Cyclophosphamide followed by Paclitaxel	- Protocol (27 Jun 2011) - Preprinted order (27 Jun 2011) - Patient Handout (01 Aug 2006)
BRAJACTT: Adjuvant Therapy for Breast Cancer using Doxorubicin and Cyclophosphamide followed by Paclitaxel and Trastuzumab	- Protocol (27 Jan 2011) - Preprinted order (01 Dec 2011) - Patient Handout (20 Oct 2006)
BRAJACTTG: Adjuvant Therapy for Breast Cancer using Dose Dense Therapy: Doxorubicin and Cyclophosphamide followed by Paclitaxel and Trastuzumab	- Protocol (29 Jun 2011) - Preprinted order (01 Dec 2011) - Patient Handout (20 Oct 2006)
UBRAJACTW: Adjuvant Therapy for Early Breast Cancer using Doxorubicin and Cyclophosphamide followed by Weekly Paclitaxel	- Protocol (29 Jun 2011) - Preprinted order (29 Jun 2011)
BRAJANAS: Adjuvant anastrozole for breast cancer	- Protocol (01 May 2009) - Preprinted order (01 May 2009)
UBRAJCAF: Adjuvant Therapy for Breast Cancer using Cyclophosphamide, Doxorubicin and Fluorouracil	- Protocol (29 Jun 2011) - Preprinted order (29 Jun 2011) - Patient Handout (19 Jun 2006)
BRAJCAF-G: Adjuvant Therapy for Breast Cancer Using Cyclophosphamide, Doxorubicin, Fluorouracil and Filgrastim (G-CSF)	- Protocol (29 Jun 2011) - Preprinted order (29 Jun 2011)
BRAJCAFPO: Adjuvant Therapy for Breast Cancer using Oral Cyclophosphamide, Doxorubicin and Fluorouracil.	- Protocol (29 Jun 2011) - Preprinted order (29 Jun 2011) - Patient Handout (16 Nov 2004)
BRAJCEF: Adjuvant therapy for breast cancer using Cyclophosphamide, Epirubicin and Fluorouracil.	- Protocol (01 Sep 2009) - Preprinted order (27 Jun 2011) - Patient Handout (01 Nov 2002)
BRAJCEFG: Adjuvant Therapy for Breast Cancer Using Cyclophosphamide, Epirubicin, Fluorouracil and Filgrastim (G-CSF).	- Protocol (29 Jun 2011) - Preprinted order (29 Jun 2011)
BRAJCMF: Adjuvant therapy for high risk breast cancer using Cyclophosphamide (IV), Methotrexate and Fluorouracil.	- Protocol (29 Jun 2011) - Preprinted order (29 Jun 2011) - Patient Handout (19 Jun 2006)
BRAJCMFPO: Adjuvant therapy for high-risk breast cancer using Cyclophosphamide (oral), Methotrexate and Fluorouracil.	- Protocol (01 Sep 2009) - Preprinted order (01 May 2009) - Patient Handout (19 Aug 2005)
BRAJDAC: Adjuvant Therapy for Breast Cancer using Cyclophosphamide, Doxorubicin and Docetaxel	- Protocol (29 Jun 2011) - Preprinted order (29 Jun 2011) - Patient Handout (01 Oct 2010)
BRAJDC: Adjuvant Therapy for Breast Cancer Using Docetaxel and Cyclophosphamide.	- Protocol (27 Jun 2011) - Preprinted order (27 Jun 2011) - Patient Handout (01 Oct 2010)
UBRAJDCT: Adjuvant Therapy for Breast Cancer Using Docetaxel, Carboplatin and Trastuzumab	- Protocol (27 Jun 2011) - Preprinted order (01 Sep 2011) - Patient Handout (01 Oct 2010)
BRAJDTFEC: Adjuvant Therapy for Breast Cancer Using Docetaxel and Trastuzumab, and Fluorouracil, Epirubicin and Cyclophosphamide.	- Protocol (27 Jun 2011) - Preprinted order (01 Sep 2011) - Patient Handout (01 Oct 2010)
BRAJEXE: Adjuvant exemestane for breast cancer.	- Protocol (01 May 2009) - Preprinted order (01 May 09)
BRAJFEC: Adjuvant Therapy for Breast Cancer Using Fluorouracil, Epirubicin and Cyclophosphamide.	- Protocol (27 Jun 2011) - Preprinted order (27 Jun 2011) - Patient Handout (01 Aug 2007)
BRAJFECD (replaced UBRAJFECD): Adjuvant Therapy for Breast Cancer Using Fluorouracil, Epirubicin and Cyclophosphamide and Docetaxel.	- Protocol (01 Feb 2012) - Preprinted order (27 Jun 2011) - Patient Handout (01 Oct 2010)
BRAJFECDT: Adjuvant Therapy for Breast Cancer using Fluorouracil, Epirubicin and Cyclophosphamide followed by Docetaxel and Trastuzumab	- Protocol (01 Feb 2012) - Preprinted order (01 Feb 2012)
BRAJLET: Adjuvant letrozole for breast cancer	- Protocol (01 May 2009) - Preprinted order (01 May 09)
BRAJLHRHT: Adjuvant therapy for breast cancer using a LHRH agonist and tamoxifen	- Protocol (01 May 2009) - Preprinted order (01 May 2009)
BRAJTAM: Adjuvant Therapy for Breast Cancer using Tamoxifen.	- Protocol (01 May 2009) - Preprinted order (01 May 2009) - Patient Handout (01 Jul 2007)
BRAJTR: Adjuvant Therapy for Breast Cancer using Trastuzumab following the Completion of Chemotherapy (Sequential).	- Protocol (01 Sep 2011) - Preprinted order (01 Sep 2011) - Patient Handout (20 Oct 2006)

LOCALLY ADVANCED TREATMENTS PROTOCOL CODE and DESCRIPTION	AVAILABLE DOCUMENTS (revision date indicated in red)
BRLAACD: Treatment of Locally Advanced Breast Cancer using Doxorubicin and Cyclophosphamide followed by Docetaxel (TAXOTERE®).	- Protocol (27 Jun 2011) - Preprinted order (27 Jun 2011) - Patient Handout (01 Oct 2010)
BRLAACDT: Treatment of Locally Advanced Breast Cancer using Doxorubicin and Cyclophosphamide followed by Docetaxel (TAXOTERE®) and Trastuzumab.	- Protocol (29 Jun 2011) - Preprinted order (01 Sep 2011) - Patient Handout (01 Oct 2010)
BRLA2: Therapy for Locally advanced breast cancer using Cyclophosphamide, Doxorubicin and Fluorouracil.	- Protocol (29 Jun 2011) - Preprinted order (29 Jun 2011)
BRLACEF: Therapy for locally advanced breast cancer using Cyclophosphamide, Epirubicin and Fluorouracil.	- Protocol (01 Sep 2009) - Preprinted order (01 May 2009) - Patient Handout (01 Nov 2002)
BRLACEFG: Therapy for Locally Advanced Breast Cancer Using Cyclophosphamide, Epirubicin, Fluorouracil and Filgrastim (G-CSF).	- Protocol (29 Jun 2011) - Preprinted order (29 Jun 2011) - Patient Handout (01 Nov 2002)

ADVANCED TREATMENTS PROTOCOL CODE and DESCRIPTION	AVAILABLE DOCUMENTS (revision date indicated in red)
BRAVA7: Palliative Therapy for Metastatic Breast Cancer using Weekly Doxorubicin	- Protocol (01 May 2009) - Preprinted order (01 May 2009)
BRAVAC: Palliative therapy for metastatic breast cancer using Doxorubicin and Cyclophosphamide.	- Protocol (27 Jun 2011) - Preprinted order (27 Jun 2011) - Patient Handout (01 Feb 2008)
BRAVABR: Palliative Therapy for Metastatic Breast Cancer using nanoparticle, albumin-bound (nab)-Paclitaxel (ABRAXANE®)	- Protocol (01 Jan 2012) - Preprinted order (27 Jun 2011)
BRAVANAS: Palliative therapy for breast cancer using Anastrozole	- Protocol (01 May 2009) - Preprinted order (01 May 2009)
BRAVCAF: Palliative Therapy for Metastatic Breast Cancer Using Cyclophosphamide, Doxorubicin and Fluorouracil	- Protocol (27 Jun 2011) - Preprinted order (27 Jun 2011) - Patient Handout (19 Jun 2006)
BRAVCAP: Therapy for Metastatic Breast Cancer Using Capecitabine	- Protocol (01 Apr 2011) - Preprinted order (16 April 2010) - Patient Handout (01 Jan 2011)
BRAVCLOD: Therapy for therapy of bone metastases in breast cancer using Oral Clodronate	- Protocol (01 Jan 2012) - Preprinted order (01 May 2009)
BRAVCMF: Palliative therapy for advanced breast cancer using Cyclophosphamide, Methotrexate and Fluorouracil	- Protocol (29 Jun 2011) - Preprinted order (29 Jun 2011) - Patient Handout (19 Jun 2006)
BRAVCMFPO: Palliative therapy for advanced breast cancer using Cyclophosphamide (oral), Methotrexate and Fluorouracil	- Protocol (01 Sep 2009) - Preprinted order (01 Feb 2011)
BRAVDCAP: Palliative Therapy for Metastatic Breast Cancer Using Docetaxel and Capecitabine. (formerly BRAVCAD)	- Protocol (01 Apr 2011) - Preprinted order (29 Jun 2011) - Patient Handout (01 Jan 2011)
BRAVDOC: Palliative therapy for metastatic breast cancer using Docetaxel	- Protocol (01 Jan 2012) - Preprinted order (27 Jun 2011) - Patient Handout (01 Oct 2010)
BRAVDOC7: Palliative Therapy for Metastatic Breast Cancer using Weekly Docetaxel	- Protocol (01 Jan 2012) - Preprinted order (27 Jun 2011) - Patient Handout (01 Feb 2008)
BRAVEXE: Palliative Therapy for Advanced Breast Cancer Using Exemestane	- Protocol (01 May 2009) - Preprinted order (01 May 2009)
BRAVGEM: Palliative Therapy for Metastatic Breast Cancer using Gemcitabine	- Protocol (01 May 2009) - Preprinted order (29 Jun 2011) - Patient handout (01 Jul 2008)
BRAVGEMD: Palliative Therapy for Metastatic Breast Cancer using Gemcitabine and Docetaxel	- Protocol (29 Jun 2011) - Preprinted order (29 Jun 2011) - Patient handout (01 Oct 2010)
BRAVGEMP: Palliative Therapy for Metastatic Breast Cancer Using Cisplatin and Gemcitabine (formerly UBRAVPG)	- Protocol (27 Jun 2011) - Preprinted order (01 Feb 2012) - Patient Handout (01 Sep 2010)
BRAVGEMT: Palliative Therapy for Metastatic Breast Cancer using Gemcitabine and Paclitaxel.	- Protocol (01 May 2009) - Preprinted order (29 Jun 2011) - Patient Handout (01 Feb 2008)
UBRAVLCAP: Therapy for Metastatic Breast Cancer Using Capecitabine and Lapatinib.	- Protocol (01 Dec 2011) - Preprinted order (04 Jul 2011)
BRAVLET: Palliative therapy for advanced breast cancer using Letrozole.	- Protocol (01 May 2009) - Preprinted order (01 May 2009)
BRAVLHRHT: Palliative therapy for breast cancer using a LHRH agonist and tamoxifen.	- Protocol (01 May 2009) - Preprinted order (01 May 2009)
BRAVMEG: Palliative Therapy for Advanced Breast Cancer Using Megestrol.	- Protocol (01 May 2009) - Preprinted order (01 May 2009)
BRAVNAV: Palliative therapy for symptomatic metastatic breast cancer using Vinorelbine.	- Protocol (1 Nov 2011) - Preprinted order (27 Jun 2011) - Patient Handout (01 Sep 2006)
BRAVPAM: Treatment of acute bone pain secondary to breast cancer metastases using Pamidronate.	- Protocol (01 Jan 2012) - Preprinted order (27 Jun 2011)
BRAVT7: Palliative Therapy for Metastatic Breast Cancer Using Weekly Paclitaxel	- Protocol (01 Jan 2012) - Preprinted order (27 Jun 2011)
BRAVTAM: Palliative Therapy for Breast Cancer Using Tamoxifen.	- Protocol (01 May 2009) -Preprinted order (01 May 2009) - Patient Handout (01 Jul 2007)
BRAVTAX: Palliative therapy for metastatic breast cancer using Paclitaxel.	- Protocol (01 Jan 2012) - Preprinted order (29 Jun 2011)
UBRAVTCAP: Palliative Therapy for Metastatic Breast Cancer using Trastuzumab and Capecitabine.	- Protocol (04 Jul 2011) - Preprinted order (01 Sep 2011)
BRAVTEST: Palliative therapy for metastatic breast cancer using testosterone enanthate.	- Protocol (01 May 2009) - Preprinted order (01 May 2009)
BRAVTPC: Palliative Therapy for Metastatic Breast Cancer using Trastuzumab, Paclitaxel and Carboplatin as First-Line Treatment for Advanced Breast Cancer.	- Protocol (29 Jun 2011) - Preprinted order (01 Sep 2011) - Patient Handout (01 Oct 2006)
BRAVTR: Palliative Therapy for Metastatic Breast Cancer using Trastuzumab.	- Protocol (27 Jun 2011) - Preprinted order (01 Sep 2011) - Patient Handout (01 Sep 2006)
BRAVTRAD: Palliative Therapy for Metastatic Breast Cancer using Trastuzumab and Docetaxel as First-Line Treatment for Advanced Breast Cancer.	- Protocol (27 Jun 2011) - Preprinted orders (01 Sep 2011)
BRAVTRAP: Palliative therapy for metastatic breast cancer using trastuzumab and paclitaxel as first-line treatment for advanced breast cancer.	- Protocol (29 Jun 2011) - Preprinted order (01 Sep 2011) - Patient Handout (01 Feb 2008)
BRAVTRNAV: Palliative therapy for metastatic breast cancer using trastuzumab and vinorelbine (REPLACED BY BRAVTRVIN 1 Nov 2011)	- Protocol (replaced by BRAVTRVIN) - Preprinted order (replaced by BRAVTRVIN) - Patient Handout (replaced by BRAVTRVIN)
BRAVTRVIN: Palliative Therapy for Metastatic Breast Cancer using Trastuzumab and Vinorelbine	- Protocol (14 Dec 2011) - Preprinted order (1 Nov 2011) - Patient Handout (1 Nov 2011)
BRINFCAF: Therapy for inflammatory breast cancer using Cyclophosphamide, Doxorubicin and Fluorouracil.	- Protocol (29 Jun 2011) - Preprinted order (29 Jun 2011)
BRINFCEF: Therapy for inflammatory breast cancer using Cyclophosphamide, Epirubicin and Fluorouracil.	- Protocol (01 Sep 2009) - Preprinted order (01 May 2009) - Patient Handout (01 Nov 2002)
BRINFCEF-G: Therapy for Inflammatory Breast Cancer Using Cyclophosphamide, Epirubicin, Fluorouracil and Filgrastim (G-CSF).	- Protocol (29 Jun 2011) - Preprinted order (29 Jun 2011)