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Chemotherapy Protocols
Head & Neck

Head & Neck

The information contained in these documents is a statement of consensus of BC Cancer Agency professionals regarding their views of currently accepted approaches to treatment. Any clinician seeking to apply or consult these documents is expected to use independent medical judgement in the context of individual clinical circumstances to determine any patient's care or treatment. Use of these documents is at your own risk and is subject to BC Cancer Agency's terms of use available at www.bccancer.bc.ca/legal.htm .

PLEASE NOTE: All links in the table below open PDF documents.

NASOPHARYNGEAL CARCINOMA
PROTOCOL CODE and DESCRIPTION		 AVAILABLE DOCUMENTS
(revision date indicated in red)
Locally advanced Disease
HNNLAPG: Induction Treatment of Locally Advanced Nasopharyngeal Cancer with Cisplatin and Gemcitabine - Protocol (27 Jun 2011)
- Preprinted order (01 Dec 2011)
- Patient Handout (29 Jul 2011)
HNNLAPRT: Treatment of Locally Advanced Nasopharyngeal Cancer with Concurrent Cisplatin and Radiation - Protocol (27 Jun 2011)
- Preprinted order (27 Jun 2011)
- Patient Handout (01 Dec 2010)
Advanced Disease
HNNAVFUFA: 5-Fluorouracil and Leucovorin for Recurrent Head and Neck Cancer (Nasopharyngeal) - Protocol (02 Dec 2010)
- Preprinted order (01 Dec 2010)
HNNAVFUP: Treatment for Advanced Nasopharyngeal Cancer of the Head and Neck using Cisplatin and Fluorouracil - Protocol (27 Jun 2011)
- Preprinted order (27 Jun 2011)
- Infusor™ – Patient Guide
- Discontinue Infusor™ from IVAD
- Discontinue Infusor™ from PICC 
HNNAVGEM: Treatment of Loco-regionally Recurrent/Metastatic Nasopharyngeal Cancer Not Amenable for Local Curative Therapy with Gemcitabine - Protocol (01 Sep 2010)
- Preprinted order (29 Jun 2011)
HNNAVP: Palliative Chemotherapy for Advanced Head and Neck Nasopharyngeal Carcinoma with Weekly Cisplatin - Protocol (29 Jun 2011)
- Preprinted order (29 Jun 2011)
HNNAVPE: Intensive Cisplatin and Etoposide Chemotherapy for Recurrent and Metastatic Head and Neck Cancer (Nasopharyngeal) - Protocol (29 Jun 2011)
- Preprinted order (29 Jun 2011)
HNNAVPG: Treatment of Locoregionally Recurrent and/or Metastatic Nasopharyngeal Cancer with Cisplatin and Gemcitabine - Protocol (29 Jun 2011)
- Preprinted order (29 Jun 2011)
UHNNAVCAP: Treatment Of Recurrent Or Metastatic Nasopharyngeal Cancer With Capecitabine - Protocol (01 Apr 2011)
- Preprinted order (01 Jul 2010)
UHNNAVPC: Treatment of Recurrent or Metastatic Nasopharyngeal Carcinoma with Carboplatin and Paclitaxel - Protocol (01 Apr 2011)
- Preprinted order (29 Jun 2011)
HNDE Therapy for recurrent and metastatic nasopharyngeal cancer using Cisplatin and Etoposide (DELETED 1 APRIL 2010)  - Protocol (01 Mar 2009)
 - Preprinted order (01 May 2009)
SQUAMOUS CELL CARCINOMA
PROTOCOL CODE and DESCRIPTION		 AVAILABLE DOCUMENTS
(revision date indicated in red)
Locally advanced disease
HNLAALTPRT: Treatment of Locally Advanced (Alternate) Head and Neck Cancer Using Cisplatin during Radiation Therapy - Protocol (01 Dec 2011)
- Preprinted order (01 Feb 2012)
- Patient Handout (01 Feb 2012)
HNLAPRT: Combined Chemotherapy (Cisplatin) and Radiation Treatment for Locally Advanced Squamous Cell Carcinoma of The Head and Neck - Protocol (01 Feb 2012)
- Preprinted order (short hydration) (01 Feb 2012)
- See regional centre's inpatient order for long hydration 
- Patient Handout (01 Feb 2012)
HNLACAFRT: Combined Chemotherapy (Carboplatin and Fluorouracil) and Radiation Treatment for Locally Advanced Squamous Cell Carcinoma of the Head and Neck - Protocol (01 Jul 2010)
- Preprinted order (29 Jun 2011)
- Patient Handout (01 Sep 2010)
UHNLACETRT: Combined Cetuximab and Radiation Treatment for Locally Advanced Squamous Cell Carcinoma of the Head and Neck - Protocol (01 Feb 2012)
- Preprinted order (01 Feb 2012)
- Patient Handout (02 Dec 2010)
UHNLADCF: Treatment of Locally Advanced Squamous Cell Carcinoma of the Head and Neck with Docetaxel, Cisplatin and Infusional Fluorouracil - Protocol (29 Jun 2011)
- Preprinted order (29 Jun 2011)
- Patient Handout (01 Sep 2010)
HNFURT: Therapy for combined modality therapy for advanced head and neck cancer using Mitomycin C, Fluorouracil and split course radiation therapy (DELETED 1 NOV 2010) - Protocol (01 Sep 2009)
- Preprinted order (01 May 2009)
- Infusor™ – Patient Guide
- Discontinue Infusor™ from IVAD
- Discontinue Infusor™ from PICC 
HNPRT: Therapy for advanced head and neck cancer using Cisplatin before or during Radiation Therapy (REPLACED BY HNLAALTPRT 1 Jan 2011) - Protocol (1 Mar 2009)
- Preprinted order (01 May 2009)
Advanced disease
HNAVFUP: Treatment of Advanced Squamous Cell Carcinoma of the Head and Neck Cancer Using Cisplatin and Fluorouracil - Protocol (27 Jun 2011)
- Preprinted order (27 Jun 2011)
- Patient Handout (01 Feb 2012)
- Infusor™ – Patient Guide
- Discontinue Infusor™ from IVAD
- Discontinue Infusor™ from PICC 
HNAVFUFA: 5-Fluorouracil and Leucovorin for Recurrent Head and Neck Cancer (Squamous Cell Carcinoma) - Protocol (01 Dec 2010)
- Preprinted order (01 Dec 2010)
HNAVM:  Treatment of Head and Neck Cancer Using Methotrexate as Standard Therapy - Protocol (27 Jun 2011
- Preprinted order (01 Feb 2012)
HNAVP: Palliative Chemotherapy for Advanced Head and Neck Squamous Cell Carcinoma with Weekly Cisplatin - Protocol (29 Jun 2011)
- Preprinted order (29 Jun 2011)
HNAVPE:  Treatment for Intensive Cisplatin and Etoposide Chemotherapy for Recurrent and Metastatic Head and Neck Cancer (Squamous Cell Carcinoma) - Protocol (29 Jun 2011)
- Preprinted order (29 Jun 2011)
UHNAVPD: Treatment of Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck with Cisplatin and Docetaxel - Protocol (29 Jun 2011)
- Preprinted order (29 Jun 2011)
UHNAVDOC: Treatment of Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck with Docetaxel - Protocol (01 Sep 2010)
- Preprinted order (29 Jun 2011)
OTHER
PROTOCOL CODE and DESCRIPTION		 AVAILABLE DOCUMENTS
(revision date indicated in red)
HNOTAMIRT:  Radioprotection in Head and Neck Radiation using Amifostine - Protocol (01 Jul 2010)
- Preprinted order (01 Jul 2010)
HNOTTSH:  Radioiodine Imaging in Patients with Thyroid Cancer using Thyrotropin Alpha - Protocol (01 Jul 2010)
- Preprinted order (01 Jul 2010)
SALIVARY TUMOURS
PROTOCOL CODE and DESCRIPTION		 AVAILABLE DOCUMENTS
(revision date indicated in red)
HNSAVFAC: Palliative Therapy for Advanced Salivary Gland Cancers Using Cyclophosphamide, Doxorubicin and Fluorouracil - Protocol (29 Jun 2011)
- Preprinted order (29 Jun 2011)
HNSAVFUP:  Treatment of Advanced Head and Neck Cancer Using Cisplatin and Fluorouracil - Protocol (27 Jun 2011)
- Preprinted order (27 Jun 2011)
HNSAVNP:  Treatment of Advanced Salivary Gland Cancers With Cisplatin and Vinorelbine - Protocol (01 Feb 2012)
- Preprinted order (01 Feb 2012)
HNSAVPAC:  Treatment of Advanced Salivary Gland Cancers With Platinum, Doxorubicin and Cyclophospahmide - Protocol (01 Feb 2012)
- Preprinted order (01 Feb 2012)
HNSAVTAM:  Treatment of Recurrent/Metastatic Salivary Gland Cancers of the Head and Neck With Tamoxifen - Protocol (01 Feb 2012)
- Preprinted order (01 Feb 2012)

RECENTLY DELETED/REPLACED PROTOCOLS
OLD PROTOCOL NAME NEW PROTOCOL NAME
HNAMIRT Replaced by HNOTAMIRT  (1 July 2010)
HNAVGEM Replaced by HNNAVGEM (1 July 2010)
HNAVPG Replaced by HNNAVPG  (1 June 2010)
HNCAFRT Replaced by HNLACAFRT  (1 July 2010)
UHNCETRT Replaced by UHNLACETRT  (1 July 2010)
HNDE Replaced by HNAVP and HNAVPE (1 Nov 2010)
HNFUFA Replaced by HNAVFUFA and HNNAVFUFA (1 Nov 2010)
HNFUP Replaced by HNAVFUP and HNNAVFUP  (1 June 2010)
HNFURT Deleted
HNLANPRT Replaced by HNNLAPRT  (1 April 2010)
HNM Replaced by HNAVM  (1 July 2010)
HNPE Replaced by HNAVPE  (1 July 2010) and HNNAVPE (1 Nov 2010)
HNPRT Replaced by HNLAALTPRT (1 Jan 2011)
HNTSH Replaced by HNOTTSH  (1 July 2010)