A.C. is a 53-year-old male diagnosed with malignant mesothelioma, scheduled to be treated with LUMMPG. The oncologist orders CISplatin on Day 1 and gemcitabine on Days 1 and 8.
Weight: 82 kg Height: 174 cm
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Lab results taken 72 hours prior to first treatment
WBC 8.6 Bilirubin 10
ANC 3.5 Alk Phos 63
Platelets 257 AST 19
Creatinine 130 LDH 123 |
1. What dose of cisplatin and gemcitabine should the oncologist prescribe, based on the calculated BSA?
- 149 mg CISplatin and 2488 mg gemcitabine [select]
- 89 mg CISplatin and 1493 mg gemcitabine [select]
- 90 mg CISplatin and 2488 mg gemcitabine [select]
- 150 mg CISplatin and 1500 mg gemcitabine [select]
2. What hydration orders should the oncologist prescribe, based on the LUMMPG protocol?
- 1000 mL NS over 60 minutes pre-hydration, with cisplatin in 1000 mL NS with 20 mEq KCl, 1 g MgSO4 and 30 g mannitol infused over 60 minutes [select]
- 500 mL NS over 60 minutes pre-hydration, with cisplatin in 500 mL NS with 10 mEq KCl, 500 mg MgSO4 and 15 g mannitol over 60 minutes [select]
- 1000 mL NS over one hour post-hydration [select]
- a) and c) [select]