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Understanding Fatigue

Reviewed: December 2006 

The symptoms of cancer fatigue include not only feeling tired - weak, worn out, drained, "wiped out" - but also leg pain, difficulty climbing stairs or walking short distances, shortness of breath after light activity, and difficulty performing ordinary tasks such as cooking, cleaning, taking a shower or making the bed.

What Causes Cancer-Related Fatigue?

The specific mechanisms involved in the development of cancer- related fatigue are not completely known, however, we do know that it is multifactoral and both physiological and psychological factors play a part.

Sometimes fatigue is related to:

  • the cancer treatment itself or medications - either to help treat the cancer or to manage the symptoms, such as pain.
  • medical causes such as dehydration, electrolyte imbalance, breathing problems, diarrhea, fever, infection, nausea/ vomiting, pain, or anemia.
  • poor appetite or nutrition.
  • worrying, anxiety, or depression.
  • too much rest
Cancer-related fatigue symptoms may include the following:

  • Feeling bored, sleepy, exhausted
  • Feeling a lack of motivation and interest in things that are normally important
  • Trouble doing the things that you normally did easily such as trouble climbing stairs or walking short distances
  • Trouble concentrating, thinking, speaking or making decisions
  • Loss of appetite
  • Lack of interest in sex
  • Feeling tired even after a good night's sleep and/or not being able to sleep at night
  • Exhaustion, apathy, lethargy
  • Generalized (whole body) weakness or tiredness
  • Sleep abnormalities
  • Irritability, impatience, sadness, changes in mood
Understanding Cancer Treatment-Related Fatigue

Facts You Should Know

  • Fatigue is the most common side effect of cancer treatment.
  • The fatigue experienced by a person with cancer is different from fatigue of everyday life. Cancer treatment-related fatigue can appear suddenly. It can be overwhelming. It is not always relieved by rest. It can last after treatment ends.
  • Cancer treatment-related fatigue can affect many aspects of a person's life. It may affect an individual's mood or emotions. It may also affect a person's ability to do usual activities. Fatigue can make it hard to concentrate.
  • Fatigue can have many causes: cancer treatment, loss of appetite, lack of exercise, and the cancer itself are all examples of probable causes of fatigue.
  • Lack of understanding within a family about cancer fatigue can lead to communication problems, resentment, and feelings of guilt.
  • For some people, careful planning of activities, exercise, and managing symptoms and side effects may help to alleviate fatigue.
  • Cancer fatigue is real. It should not be ignored. Talk to your oncology nurse about what can be done to preserve quality in your life.
The BC Cancer Agency maintains a database on commonly used unconventional therapies available to cancer patients.