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Publications
2007
- JJ Spinelli, CH Ng, JP Weber, JM Connors, RD Gascoyne, AS Lai, AR Brooks-Wilson, ND Le, BR Berry, RP Gallagher. Organochlorines and risk of non-Hodgkin lymphoma. International Journal of Cancer. 121:2585-814.
- TK Lee, AS Brazier, JA Shoveller, RP Gallagher. Sun-related behavior after a diagnosis of cutaneous malignant melanoma. Melanoma Research. 17:51-5.
- S Gill, AW Blackstock, RM Goldberg. Colorectal Cancer. Mayo Clinic Proceedings. 82:114-29.
- UO Hafeli, J Unnithan, GJ Pauer, RA Prayson. Fibrin glue system for adjuvant brachytherapy of brain tumors with 188Re and 186Re-labeled microspheres. European Journal of Pharmaceutics and Biopharmaceutics. 65:282-8.
- TP Buys, R Chari, EH Lee, M Zhang, C Macaulay, S Lam, WL Lam, V Ling. Genetic changes in the evolution of multidrug resistance for cultured human ovarian cancer cells. Genes Chromosomes Cancer. 46:1069-79.
- RJ Deleeuw, A Zettl, E Klinker, E Haralambieva, M Trottier, R Chari, Y Ge, RD Gascoyne, A Chott, HK Muller-Hermelink, WL Lam. Whole-genome analysis and HLA genotyping of enteropathy-type T-cell lymphoma reveals 2 distinct lymphoma subtypes. Gastroenterology. 132:1902-11.
- KK Wong, RJ deLeeuw, NS Dosanjh, LR Kimm, Z Cheng, DE Horsman, C MacAulay, RT Ng, CJ Brown, EE Eichler, WL Lam. A comprehensive analysis of common copy-number variations in the human genome. The American Journal of Human Genetics. 80:91-104.
- WW Lockwood, BP Coe, AC Williams, C MacAulay, WL Lam. Whole genome tiling path array CGH analysis of segmental copy number alterations in cervical cancer cell lines. International Journal of Cancer. 120:436-43.
- TP Buys, R Chari, EH Lee, M Zhang, C Macaulay, S Lam, WL Lam, V Ling. Genetic changes in the evolution of multidrug resistance for cultured human ovarian cancer cells. Genes Chromosomes Cancer. 46:1069-79.
- F Taghizadeh, MJ Tang, IT Tai. Synergism between vitamin D and secreted protein acidic and rich in cysteine-induced apoptosis and growth inhibition results in increased susceptibility of therapy-resistant colorectal cancer cells to chemotherapy. Molecular Cancer Therapeutics. 6:309-17.
- DS Luciani, P Ao, X Hu, GL Warnock, JD Johnson. Voltage-gated Ca(2+) influx and insulin secretion in human and mouse beta-cells are impaired by the mitochondrial Na(+)/Ca(2+) exchange inhibitor CGP-37157. European Journal of Pharmacology. 576:18-25.
- JR Lakey, T Kin, GL Warnock, AM Shapiro, P Tsapogas, S Imes, GS Korbutt, NM Kneteman, RV Rajotte, EA Ryan. Long term graft function after allogeneic islet transplantation. Cell Transplant. 16:441-6.
- MA Fung, GL Warnock, Z Ao, P Keown, M Meloche, RJ Shapiro, S Ho, D Worsley, GS Meneilly, K Al Ghofaili, SE Kozak, SO Tong, M Trinh, L Blackburn, RM Kozak, BA Fensom, DM Thompson. The effect of medical therapy and islet cell transplantation on diabetic nephropathy: an interim report. Transplantation. 84:17-22.
- YH Liao, CB Verchere, GL Warnock. Adult stem or progenitor cells in treatment for type 1 diabetes: current progress. Canadian Journal of Surgery. 50:137-42.
- DM Thompson, MA Fung, GL Warnock. Islet Transplantation. The New England Journal of Medicine. 356:964-5.
- WH Dragowska, M Verreault, DT Yapp, C Warburton, L Edwards, EC Ramsay, LA Huxham, AI Minchinton, K Gelmon, MB Bally. Decreased levels of hypoxic cells in gefitinib treated ER(+) HER-2 overexpressing MCF-7 breast cancer tumors are associated with hyperactivation of the mTOR pathway: therapeutic implications for combination therapy with rapamycin. Breast Cancer Research and Treatment. 106:319-31.
- DT Yapp, J Woo, A Kartono, J Sy, T Oliver, KA Skov, CJ Koch, H Adomat, WH Dragowska, L Fazli, T Ruth, MJ Adam, D Green, M Gleave. Non-invasive evaluation of tumour hypoxia in the Shionogi tumour model for prostate cancer with 18F-EF5 and positron emission tomography. BJU International, British Journal of Urology. 99:1154-60.
2006
- SSW Ng, A Sparreboom, Y Shaked, C Lee, S Man, N Desai, P Soon-Shiong, WD Figg, RS Kerbel. Influence of formulation vehicle on metronomic taxane chemotherapy: albumin-bound versus cremophor EL-based paclitaxel. Clinical Cancer Research. 12:4331-8.
- PT Kim, JC Su, AK Buczkowski, DF Schaeffer, SW Chung, CH Scudamore, SG Ho. Computed tomography and angiographic interventional features of ruptured hepatocellular carcinoma: pictorial essay. Canadian Association of Radiologists Journal. 57:159-68.
- AK Buczkowski, PT Kim, SG Ho, DF Schaeffer, SI Lee, DA Owen, AH Weiss, SW Chung, CH Scudamore. Multidisciplinary management of ruptured hepatocellular carcinoma. Journal of Gastrointestinal Surgery. 10:379-86.
- PA Kanetsky, TR Rebbeck, AJ Hummer, S Panossian, BK Armstrong, A Kricker, LD Marrett, RC Millikan, SB Gruber, HA Culver, R Zanetti, RP Gallagher, T Dwyer, K Busam, L From, U Mujumdar, H Wilcox, CB Begg, M Berwick. Population-based study of natural variation in the melanocortin-1 receptor gene and melanoma. Cancer Research. 66:9330-7.
- M Berwick, I Orlow, AJ Hummer, BK Armstrong, A Kricker, LD Marrett, RC Millikan, SB Gruber, H Anton-Culver, R Zanetti, RP Gallagher, T Dwyer, TR Rebbeck, PA Kanetsky, K Busam, L From, U Mujumdar, H Wilcox, CB Begg, GEM Study Group. The prevalence of CDKN2A germ-line mutations and relative risk for cutaneous malignant melanoma: an international population-based study. Cancer Epidemiology Biomarkers & Prevention. 15:1520-5.
- N Rothman, CF Skibola, SS Wang, G Morgan, Q Lan, MT Smith, JJ Spinelli, E Willett, S De Sanjose, P Cocco, SI Berndt, P Brennan, A Brooks-Wilson, S Wacholder, N Becker, P Hartge, T Zheng, E Roman, EA Holly, P Boffetta, B Armstrong, W Cozen, M Linet, FX Bosch, MG Ennas, TR Holford, RP Gallagher, S Rollinson, PM Bracci, JR Cerhan, D Whitby, PS Moore, B Leaderer, A Lai, C Spink, S Davis, R Bosch, A Scarpa, Y Zhang, RK Severson, M Yeager, S Chanock, A Nieters. Genetic variation in TNF and IL10 and risk of non-Hodgkin lymphoma: a report from the InterLymph Consortium. The Lancet Oncology. 7:27-38.
- D Renouf, S Gill. Capecitabine-induced Cerebellar Toxicity. Clinical Colorectal Cancer. 6:70-1.
- ME Hayden, UO Hafeli. Magnetic bandages for targeted delivery of therapeutic agents. Journal of Physics - Condensed Matter. 18:S2877-91.
- P Kozlowski, SD Chang, EC Jones, KW Berean, H Chen, SL Goldenberg. Combined Diffusion Weighted and Dynamic Contrast Enhanced MRI for prostate cancer diagnosis - correlation with biopsy and histopathology. Journal of Magnetic Resonance Imaging. 24:108-13.
- BP Coe, WW Lockwood, L Girard, R Chari, C Macaulay, S Lam, AF Gazdar, JD Minna, WL Lam. Differential disruption of cell cycle pathways in small cell and non-small cell lung cancer. British Journal of Cancer. 94:1927-35.
- IM Wilson, JJ Davies, M Weber, CJ Brown, CE Alvarez, C MacAulay, D Schubeler, WL Lam. Epigenomics: mapping the methylome. Cell Cycle. 5:155-8.
- MM Gottesman, V Ling. The molecular basis of multidrug resistance in cancer: the early years of P-glycoprotein research. FEBS Letts. 580:998-1009.
- DN Waterhouse, KA Gelmon, R Klasa, K Chi, D Huntsman, E Ramsay, E Wasan, L Edwards, C Tucker, J Zastre, YZ Wang, D Yapp, W Dragowska, S Dunn, S Dedhar, MB Bally. Development and assessment of conventional and targeted drug combinations for use in the treatment of aggressive breast cancers. Current Cancer Drug Targets. 6:455-89.
- JC Cutz, J Guan, J Bayani, M Yoshimoto, H Xue, M Sutcliffe, J English, J Flint, J LeRiche, J Yee, JA Squire, PW Gout, S Lam, YZ Wang. Establishment in severe combined immunodeficiency mice of subrenal capsule xenografts and transplantable tumor lines from a variety of primary human lung cancers: potential models for studying tumor progression-related changes. Clinical Cancer Research. 12:4043-54.
- JD Johnson, E Bernal-Mizrachi, EU Alejandro, Z Han, TB Kalynyak, H Li, JL Beith, J Gross, GL Warnock, RR Townsend, MA Permutt, KS Polonsky. Insulin protects islets from apoptosis via Pdx1 and specific changes in the human islet proteome. Proceedings of the National Academy of Sciences. 103:19575-80.
- D Ou, X Wang, DL Metzger, Z Ao, P Pozzilli, RF James, L Chen, GL Warnock. Suppression of human T-cell responses to beta-cells by activation of B7-H4 pathway. Cell Transplantation. 15:399-410.
2005
- GJ McKenna, A Meneghetti, YL Chen, AL Mui, C Ong, CH Scudamore, WR McMaster, DA Owen, SW Chung. Predictive value of lymph node and tumor matrix metalloproteinase expression in the analysis of metastatic periampullary tumors. Journal of Surgical Oncology. 90:239-46.
- CB Begg, I Orlow, AJ Hummer, BK Armstrong, A Kricker, LD Marrett, RC Millikan, SB Gruber, H Anton-Culver, R Zanetti, RP Gallagher, T Dwyer, TR Rebbeck, N Mitra, K Busam, L From, M Berwick, Genes Environment and Melanoma Study Group. Lifetime risk of melanoma in CDKN2A mutation carriers in a population-based sample. Journal of the National Cancer Institute. 97:1507-15.
- RP Gallagher, TK Lee. Keynote comment: sun exposure--cause or prevention? Lancet Oncology. 6:634-5.
- PR Band, ND Le, AC MacArthur, R Fang, RP Gallagher. Identification of occupational cancer risks in British Columbia: a population-based case-control study of 1129 cases of bladder cancer. Journal of Occupational and Environmental Medicine. 47:854-8.
- C Ho, K Ng, S OReilly, S Gill. Outcomes in Older Patients with Advanced Colorectal Cancer: A Population-Based Analysis. Clinical Colorectal Cancer. 5:279-82.
- S Gill, NM Lindor, LJ Burgart, R Smalley, O Leontovich, AJ French, RM Goldberg, DJ Sargent, JR Jass, JL Hopper, MA Jenkins, J Young, MA Barker, MD Walsh, AR Ruszkiewicz, SN Thibodeau. Isolated loss of PMS2 expression in colorectal cancers: frequency, patient age, and familial aggregation. Clinical Cancer Research. 11:6466-71.
- SR Alberts, NR Foster, RF Morton, J Kugler, P Schaefer, M Wiesenfeld, TR Fitch, P Steen, GP Kim, S Gill. PS-341 and gemcitabine in patients with metastatic pancreatic adenocarcinoma: a North Central Cancer Treatment Group (NCCTG) randomized phase II study. Annals of Oncology. 16:1654-61.
- S Gill, RM Goldberg. Duration of Adjuvant Chemotherapy for Colon Cancer: Are We Overtreating our patients? Nature Clinical Practice Oncology. 2:276-7.
- S Gill, FA Sinicrope. Colorectal Cancer Prevention - Is an ounce of prevention worth a pound of cure? Seminars in Oncology. 32:24-34.
- E Algur, RM Macklis, UO Hafeli. Synergistic cytotoxic effects of zoledronic acid and radiation in human prostate cancer and myeloma cell lines. International Journal of Radiation Oncology, Biology, Physics. 61:535-42.
- P Kozlowski, J Wong, SL Goldenberg. Serial Tumour Blood Flow Measurements in the Androgen Dependent and Androgen Independent Shionogi Tumour Model. British Journal of Urology. 95:644-649.
- ES Guns, X Xie, M Fedoruk, C Madera, S Cowell, LD Mayer, K Skov, ME Gleave, P Kozlowski. pH modulation using CsCl enhances therapeutic effects of vitamin D in LNCaP tumour bearing mice. Prostate. 64:316-22.
- P Lam, R Wang, V Ling. Bile acid transport in sister of P-glycoprotein (ABCB11) knockout mice. Biochemistry. 44:12598-605.
- IT Tai, M Dai, DA Owen, LB Chen. Genome-wide expression analysis of therapy-resistant tumors reveals SPARC as a novel target for cancer therapy. The Journal of Clinical Investigation. 115:1492-502.
- IT Tai, M Dai, LB Chen. Periostin induction in tumor cell line explants and inhibition of in vitro cell growth by anti-periostin antibodies. Carcinogenesis. 26:908-15.
- GJ McKenna, A Meneghetti, YL Chen, AL Mui, C Ong, CH Scudamore, WR McMaster, DA Owen, SW Chung. Predictive value of lymph node and tumor matrix metalloproteinase expression in the analysis of metastatic periampullary tumors. Journal of Surgical Oncology. 90:239-46.
- Y Wang, H Xue, JC Cutz, J Bayani, NR Mawji, WG Chen, LJ Goetz, SW Hayward, MD Sadar, CB Gilks, PW Gout, JA Squire, GR Cunha, YZ Wang. An orthotopic metastatic prostate cancer model in SCID mice via grafting of a transplantable human prostate tumor line. Laboratory Investigation. 85:1392-404.
2004
- SSW Ng, WD Figg, A Sparreboom. Taxane-mediated antiangiogenesis: influence of formulation vehicles and binding proteins. Cancer Research. 64:821-4.
- SSW Ng, M Gutschow, K Eger, WD Figg. Antitumor effects of thalidomide analogues in human prostate cancer xenografts implanted in immunodeficient mice. Clinical Cancer Research. 10:4192-97.
- S Gill, CL Loprinzi, DJ Sargent, SD Thomé, SR Alberts, DG Haller, J Benedetti, G Francini, LE Shepherd, J Francois Seitz, R LaBianca, W Chen, SS Cha, MP Heldebrant, RM Goldberg. Pooled Analysis of 5-FU Based Adjuvant Therapy for Stage II and III Colon Cancer: Who Benefits and by How Much? Journal of Clinical Oncology. 22:1797-806.
- JQ Cao, YX Wang, JF Yu, JY Xia, CF Zhang, DZ Yin, UO Hafeli. Preparation and radiolabeling of surface-modified magnetic nanoparticles with rhenium-188 for magnetic targeted radiotherapy. Journal of Magnetism and Magnetic Materials. 277:165-74.
- S Gupta, VM Adhami, M Subbarayan, GT MacLennan, JS Lewin, UO Hafeli, PF Fu, H Mukhtar. Suppression of prostate carcinogenesis by dietary supplementation of celecoxib in transgenic adenocarcinoma of the mouse prostate model. Cancer Research. 64:3334-43.
- J McNab, A Yung, P Kozlowski. Tissue Oxygen Tension Measurements in the Shionogi Model of Prostate Cancer using F19 NMR and MRI. MAGMA. 17:288-95.
- JA Sheps, S Ralph, Z Zhao, DL Baillie, V Ling. The ABC transporter gene family of Caenorhabditis elegans has implications for the evolutionary dynamics of multidrug resistance in eukaryotes. Genome Biology. 5:R1-15.
- AS Ishkanian, CA Malloff, SK Watson, RJ DeLeeuw, B Chi, BP Coe, A Snijders, DG Albertson, D Pinkel, MA Marra, V Ling, C MacAulay, WL Lam. A tiling resolution DNA microarray with complete coverage of human genome. Nature Genetics. 36:299-303.
- GR Cunha, W Ricke, A Thomson, PC Marker, G Risbridger, SW Hayward, YZ Wang, AA Donjacour, T Kurita. Hormonal, cellular, and molecular regulation of normal and neoplastic prostatic development. The Journal of Steroid Biochemistry and Molecular Biology. 92:221-36.
- K Skov, H Adomat, M Bowden, W Dragowska, M Gleave, CJ Koch, J Woo, DT Yapp. Hypoxia in the androgen-dependent Shionogi model for prostate cancer at three stages. Radiation Research. 162:547-53.
- WH Dragowska, C Warburton, DT Yapp, AI Minchinton, Y Hu, DN Waterhouse, K Gelmon, K Skov, J Woo, D Masin, LA Huxham, AH Kyle, MB Bally. HER-2/neu overexpression increases the viable hypoxic cell population within solid tumors without causing changes in tumor vascularization. Molecular Cancer Research. 2:606-19.
2003
- GR Macpherson, SSW Ng, S Forbes, G Melillo, T Karpova, J McNally, A Martinez, F Cuttitta, DK Price, WD Figg. Antiangiogenic activity of human endostatin is HIF-1-independent in vitro and sensitive to timing of treatment in a human saphenous vein assay. Molecular Cancer Therapeutics. 2:845-54.
- SSW Ng, M Gutschow, M Weiss, S Hauschildt, TK Hecker, U Teubert, FA Luzzio, EA Kruger, K Eger, WD Figg. Antiangiogenic activity of N-substituted and tetrafluorinated thalidomide analogues. Cancer Research. 63:3189-94.
- S Gill, RR Thomas, RM Goldberg. New Targeted Therapies in Gastrointestinal Cancers. Current Treatment Options in Oncology. 4:393-403.
- S Gill, A Shah, N Le, EF Cook, EM Yoshida. Asian Ethnicity-Related Differences in Gastric Cancer Presentation and Outcomes Among Patients Treated at a Canadian Cancer Center. Journal of Clinical Oncology. 21:2070-6.
- JF Yu, UO Hafeli, M Sands, YH Dong. Y-90-oxine-ethiodol, a potential radiopharmaceutical for the treatment of liver cancer. Applied Radiation and Isotopes. 58:567-73.
- M Subbarayan, UO Hafeli, DK Feyes, J Unnithan, SN Emancipator, H Mukhtar. A simplified method for preparation of Tc-99m-annexin V and its biologic evaluation for in vivo imaging of apoptosis after photodynamic therapy. Journal of Nuclear Medicine. 44:650-6.
- FE Davies, AM Dring, C Li, AC Rawstron, MA Shammas, SM OConnor, JA Fenton, T Hideshima, D Chauhan, IT Tai, E Robinson, D Auclair, K Rees, D Gonzalez, AJ Ashcroft, R Dasgupta, C Mitsiades, N Mitsiades, LB Chen, WH Wong, NC Munshi, GJ Morgan, KC Anderson. Insights into the multistep transformation of MGUS to myeloma using microarray expression analysis. Blood. 102:4504-11.
- GR Cunha, SW Hayward, YZ Wang, WA Ricke. Role of the stromal microenvironment in carcinogenesis of the prostate. International Journal of Cancer. 107:1-10.
2002
- SSW Ng, MS Tsao, T Nicklee, DW Hedley. Effects of the epidermal growth factor receptor inhibitor OSI-774 on downstream signalling pathways and apoptosis in human pancreatic adenocarcinoma. Molecular Cancer Therapeutics. 1:777-83.
- SSW Ng, M Brown, WD Figg. Thalidomide, an antiangiogenic agent with clinical activity in cancer. Biomedicine & pharmacotherapy. 56:194-9.
- PW Hochachka, JL Rupert, SL Goldenberg, ME Gleave, P Kozlowski. Going malignant: The hypoxia connection in prostate cancer. BioEssays. 24:749-57.
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