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Angiocentric Immunoproliferative Lesion

The terms angiocentric immunoproliferative lesion and angiocentric lymphoma have become obsolete, at least in part because as many as 1/3 of the lymphomas that belong in this category are not angiocentric. The lesions previously included in these and closely related categories are shown in the table below along with the current correct name for each condition. The correspondence between the old and new names is not exact because progress in lymphoma classification has also led to the recognition that some lesions previously assigned to this category actually represent variants of other recognized lymphoma subtypes. Treatment recommendations for each of these diseases are described in their own specific sections, which should be consulted.

Old NameCurrent Name
Angioimmunoblastic lymphadenopathy with dysproteinemia

  Peripheral T cell lymphoma AILD-type

Lymphomatoid granulomatosis Diffuse large B cell lymphoma (this is a variant form of T-cell rich B-cell lymphoma, is usually associated with Epstein-Barr virus and is most often found in the lung, skin or CNS)
Lethal midline granuloma (polymorphic reticulosis) Peripheral T cell lymphoma
nasal T/NK or true T subtype

SOURCE: Angiocentric Immunoproliferative Lesion ( )
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