Skip to main content

Angiofollicular Lymph node hyperplasia (Castleman's Disease)

Angiofollicular lymph node hyperplasia occurs as two histologic subtypes - the hyaline-vascular type and the plasma cell variant. The hyaline-vascular type is usually localized and not associated with systemic symptoms and is best managed with complete surgical excision. The plasma cell variant accounts for approximately 10% of cases and is often accompanied by systemic symptoms. Management of this entity should be discussed with a medical oncology member of the Lymphoma Tumour Group at one of the BCCA Centers. A multicentric form of Castleman's disease exists with histologic features that overlap both hyaline-vascular and plasma cell variants. The malignant potential of this systemic disease is uncertain and management should be individualized.

SOURCE: Angiofollicular Lymph node hyperplasia (Castleman's Disease) ( )
Page printed: . Unofficial document if printed. Please refer to SOURCE for latest information.

Copyright © BC Cancer. All Rights Reserved.

    Copyright © 2024 Provincial Health Services Authority