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All these criteria must be present:

  • Biopsy proof of a plasma cell tumour
  • No lytic bone lesions except the tumour itself
  • Bone marrow plasma cell proportion less than 10%
  • For solitary plasmacytoma of bone: no significant PET scan or CT scan abnormality at another site

A serum and/or urine monoclonal paraprotein may be present. Usually the uninvolved immunoglobulin levels are normal.​​

SOURCE: Diagnosis ( )
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