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Research

The specific objective of the ROE (Research Outcomes and Evaluation Committee) Research Project Program is to identify and enable projects that support the mandates of the Surgeon Network. 

This program can be used to support a variety of initiatives including obtaining data for early stage pilot or feasibility studies as well as communication or education initiatives.  While the BC Cancer Surgeon Network does not provide direct funding in the form of grants, it will provide in-kind administrative and organizational support for approved projects.  


Project Application and Guidelines

Eligibility Requirements

  • All members of the BC Cancer Surgeon Network are invited to apply.  
  • The project leader in the project must be a surgeon practicing oncology.  External participants may be included in the project proposal as co-applicants. 
  • The proposed project must be directed towards supporting one of the four functions of the BC Cancer Surgeon Network.

View the complete Project Proposal Guidelines here


There is a two-stage application process:


Stage 1: Feasibility Application


A Project Feasibility Application must be submitted by email to the BC Cancer Surgeon Network Research and Outcomes Evaluation Committee (ROEC@bccancer.bc.ca). The Feasibility Proposal will be reviewed by the ROE Committee Chair and Coordinator. If approved, applicants will be invited to submit a full application. Applicants will be notified within 4-6 weeks.


Please provide the following information:

  • Title of Proposed Project
  • Name of Project Leader, Team Members and Contact Information
  • Brief description of proposed project, including expected duration/timeline (maximum 1 page)

Stage 2: Submission of Full Project Proposal (invited applications only)


The full application will include the following:


  1. Cover page: including the proposed title of the project, project leader (name affiliation, telephone, fax, e-mail) and team members (name affiliation, telephone, fax, e-mail).
  2. Project Overview: (half page maximum) stating the objectives of project and the approach, highlighting the expected significance of the work. This must indicate how the research proposal fits with the objectives of the BC Cancer Surgeon Network.
  3. Commitment to Project: Indicate the number of hours total that the project leader and co-investigators intend to devote to the project described in the present application. Also indicate any other resources that you will commit to this project, e.g. graduate student time, administrative assistant time.
  4. Resources Requested: Estimate how much support you anticipate that you will require from the BC Cancer Surgeon Network for this project. Please be as specific as possible, for example, indicate what kind of support you will require and the estimated number of hours. For example, data entry, 20 hours.
  5. Duration: Indicate the expected duration of this project, including any relevant milestone or deadlines. Please include any submission deadlines for meetings or grants.
  6. Project Proposal: Limited to a maximum of two pages, with one additional page for figures if necessary. Minimum acceptable font size is 12 point. State the project objectives; background and significance of project; relevance of this project and implications for the improvement of surgical oncology; outline of the research plan, including methodology used; clear exclusion/inclusion criteria, if relevant; criteria to measure the success of the project; plans to disseminate results (proposed journals or meetings).
  7. Short CV of applicant(s):Include the following:
    • Address and current position of the applicant, indicating start date in that position.
    • Publication record of applicant
    • List of all grants currently held and applied for, including the source of funding, time period of funding, grant title and the amount of funding.
    • A statement of the relationship of this project to these other ongoing projects and grants

Please submit the proposal electronically to the BC Cancer Surgeon Network Research and Outcomes Evaluation Committee Coordinator at ROEC@bccancer.bc.ca


Contact Information 
Colleen McGahan, MSc
ROE Committee Coordinator
Biostatistician, BC Cancer Surgeon Network
Tel: 604-877-6000 Ext.3068
Email: ROEC@bccancer.bc.ca
 
2017 Publications
 
McKevitt E, Brown CJ, McGahan CE, Bakos B.  BC Surgical Practice for Breast Cancer Report.  
 
Scott SA, Van der Zanden C, Cai E, McGahan CE, Kwon JS. Prognostic significance of peritoneal cytology in low-intermediate risk endometrial cancer.  Gynecologic Oncology. 2017. May;145(2): 262–268
 
Eng J, Baliski C, McGahan C, Cai E. Completeness of breast cancer operative reports in a community care setting. Breast. 2017. Oct; 35:91-97
 
 
2016 Publications

McColl, RJ, McGahan CE, Cai E, Olson R, Cheung WY, Raval MJ, Phang PT, Karimuddin AA, Brown CJ. Impact of Hospital Volume on Quality Indicators for Rectal Cancer Surgery in BC. Am J Surg. 2016. Aug;212(2).

Hughes, L., Hamm, J., McGahan, C., Baliski, C. Surgeon Volume, Patient Age, and Tumor-Related Factors Influence the Need for Re-Excision After Breast-Conserving Surgery. Ann Surg Oncol (2016). doi:10.1245/s10434-016-5602-8.
 
 
Leon-Carlyle M, Brown JA, Hamm J, Phang PT, Raval MJ, Brown CJ. The accuracy of endorectal ultrasound in staging rectal lesions in patients undergoing transanal endoscopic microsurgery. American Journal of Surgery. Sept(2016). 212(3):455-60.

2014 Publications 

Christopher Baliski, Colleen E. McGahan, Caitlyn M. Liberto, Sandra Broughton, Susan Ellard, Marianne Taylor, Janet Bates, Anky Lai. Influence of nurse navigation on wait times for breast cancer care in a Canadian regional cancer center. The American Journal of Surgery. May 2014; 207 (5): 686-692.

Jutzi L, Russell D, Ho S & Kwon JS. The role of palliative colorectal stents in gynaecologic malignancy. Gynecologic Oncology. 2014;134:566-9. The volume is 134, issue 3.

Kwon JS, McGahan C, Dehaeck U, Santos J, Swenerton K, Carey MS. The Significance of Combination Chemotherapy in Epithelial Ovarian Cancer. Int J Gynecol Cancer. 2014 Feb;24(2):226-32.

2013 Publications

Faulds J, McGahan C, Phang PT, Raval M, Brown C. Differences Between Referred and Non-Referred Patients in Cancer Research. Can J Surg 2013 56(5)E136-E141

Dehaeck U, McGahan CE, Santos JL, Carey MS, Swenerton KD, Kwon JS. The Impact of Geographic Variations in Treatment on Outcomes in Ovarian Cancer. Int J Gynecol Cancer. 2013 Feb;23(2):282-7.

2012 Publications 

Aslani N, Lobo-Prabhu K, Heidary B, Phang T, Raval MJ, Brown CJ.  Outcomes of laparoscopic colon cancer surgery in a population-based cohort in British Columbia: are they are good as the clinical trials? The American Journal of Surgery. Oct 2012; 204(4): 411-15.
 
 
Shaila Merchant, Rona Cheifetz, Margaret Knowling, Fareeza Khurshed and Colleen McGahan. Practice referral patterns and outcomes in patients with primary retroperitoneal sarcoma in British Columbia. The American Journal of Surgery. May 2012; 203 (5): 632-638.

Eeson, G., Chang, N., McGahan, C. E., Khurshed, F., Buczkowski, A. K., Scudamore, C. H., Warnock, G. L. and Chung, S. W. Determination of factors predictive of outcome for patients undergoing a pancreaticoduodenectomy of pancreatic head ductal adenocarcinomas. HPB. 2012; 14: 310–316. 

Liberto C, Baliski C, McGahan C, Broughton S, Taylor M. Comparison of Breast Cancer Treatment Wait Times in the Southern Interior BC in 2006 and 2010. Canadian Journal of Surgery. 2012; 55 (supp): 140 (abstract).

2011 Publications 

P. Terry Phang, Ryan Woods, Carl J. Brown, Manoj Raval, Rona Cheifetz and Hagen Kennecke. Effect of systematic education courses on rectal cancer treatments in a population. The American Journal of Surgery. 2011; 201: 640–644.

2010 Publications 

P. Terry Phang, Rona Cheifetz, C.J. Brown, Manoj Raval. Revisiting rectal cancer management in British Columbia. BCMJ. December 2010; 52 (10): 510-551.

P. Terry Phang, Colleen E. McGahan, Greg McGregor, John K. MacFarlane, Carl J. Brown, Manoj J. Raval, Rona Cheifetz and John H. Hay. Effects of change in rectal cancer management on outcomes in British Columbia. Canadian Journal of Surgery. 2010; 53 (4): 225-231. 

Phang PT. Evolving rectal cancer management in BC. Canadian Journal of Surgery. 2010; 53: 222-224.

2007 Publications

Pinsk I, Phang PT. Total mesorectal excision and management of rectal cancer. Expert Rev Anticancer Therapy. 2007; 7:1395-1403.

2006 Publications

Cheifetz R, Phang PT. Evaluating learning and knowledge retention after a continuing medical education course on total mesorectal excision for surgeons. American Journal of Surgery. 2006; 191: 687-690.

2004 Publications

Phang PT. TME techniques. Canadian Journal of Surgery. 2004; 47: 130-137.

2003 Publications

P. Terry Phang, Martina Strack, Barbara Poole. Proposal to improve rectal cancer outcomes in BC. BCMJ, September, 2003; 45 (7):330-335.

Phang PT, MacFarlane J, Taylor R, Cheifetz R, Davis N, Hay J, et al. Practice patterns and appropriateness of care for rectal cancer management in BC. BCMJ. Sept 2003;45(7):324-329. 

Phang PT, Law J, Toy E, Speers C, Paltiel C, Coldman A. Pathology audit of 1996 and 2000 reporting for rectal cancer in BC. BCMJ. Sept 2003; 45(7):319-323. 

Phang P, MacFarlane J, Taylor R, Cheifetz R, Davis N, Hay J, et al. Effect of emergent presentation on outcome from rectal cancer management. American Journal of Surgery, 2003; 185(5):450-454. 

Richard C, Phang P, McLeod R, Group CAoGSEBRiS. Canadian Association of General Surgeons Evidence Based Reviews in Surgery. 5. Need for preoperative radiation in rectal cancer. Preoperative radiotherapy combined with total mesorectal excision for resectable rectal cancer. Canadian Journal of Surgery. Feb. 2003; 46(1):54-56.   

2002 Publications

Phang PT, MacFarlane J, Taylor RH, et al. Effects of positive resection margin and tumor distance from anus on rectal cancer treatment outcomes. American Journal of Surgery.  2002; 183:504-508.
 

Cystectomy outcomes based on surgeon and location case volume in BC (Dr. Peter Black)


Radical cystectomy is the standard of care for all muscle invasive bladder cancer and for non-muscle invasive bladder cancer resistant to intravesical therapy. This study's central objective is to explore the survival outcomes of radical cystectomy according to surgeon and hospital case volume in BC between 2002 and 2012. It aims to examine, using the CIHI DAD, the relationship between readmission rates and overall survival on the one hand, and surgeon and hospital case volume on the other hand, while controlling for clinicopathologic variables. The team is currently in the process of gaining access to the staging data from the various health authorities, which will then need to be linked to the CIHI data. 


Can we do less invasive surgery for patients receiving neoadjuvant treatment for breast cancer? (Dr. Elaine McKevitt)
 

The primary objective of the study is to determine how many patients are having breast conserving surgery or sentinel node biopsy following NAT. The secondary objective of the study is to identify a group of patients that would be good candidates for breast conserving surgery and sentinel node biopsy based on tumor characteristics. The third objective of the study is to see if how many additional patients could be eligible for breast conserving surgery or sentinel node biopsy if NAT was used.

 
 
Can we abandon staging the axilla in patients over 70 years with ER positive breast cancer? (Dr. Elaine McKevitt)
 

The primary objective of the study is to determine how many patients would have a change in management if we did not surgically stage the axilla in patients 70 and over with ER positive breast cancer.  The secondary objective of the study is to identify a group of patients that would be low risk for axillary nodal metastasis and may be able to be spared surgical staging of the axilla.

 
 
Decreasing re-excisions after breast conserving surgery in higher volume surgeons: more accurate or just more? (Dr. Chris Baliski)
 

A recent report from the Canadian Institute of Health Information (CIHI), suggested there is wide variations in the provision of breast conserving surgery in Canada, with British Columbia having higher than average mastectomy rates.(1) This has led to questions as to the quality of surgery being provided in our province. 

 
 
Does MMR status in endometrial cancer influence response to adjuvant therapy? (Dr. Janice Kwon)
 

The objective of our study is to determine if there are different response rates to adjuvant therapy among women with MMR-deficient endometrial cancers compared to those with MMR-proficient cancers. In patients with Lynch-associated colorectal cancer, multiple studies have shown that deficient MMR is associated with a higher response to 5-FU-based chemotherapy and favourable prognosis. If the same principle is true for MMR deficient endometrial tumors, this will have implications on the way we treat these cancers. Currently, we treat all endometrial cancers using same algorithm of surgery followed by radiation and/or platinum-based chemotherapy based on conventional pathological parameters (such as histotype, grade, and myometrial invasion), regardless of MMR status.

 
 
Effect of surgical procedures on PROs (Dr. Chris Baliski)

The objective of the study is to obtain experience with the collection of PRO’s including: The expected patient survey response rate, understanding the utility of the BREAST-Q measurement tool, to obtain experience with the BREAST-Q scoring tool, and to understand the barriers related to future prospective collection of PRO’s

 

 

Effect of surgeon case volume on PROs for BCS patients only (Dr. Chris Baliski)

 

The objective of the study would be to use the BREAST-Q to identify: PRO's associated with BCS, mastectomy, or mastectomy + reconstruction, Identify patient, disease, and treatment related factors influencing PRO's, and to Identify any procedure or surgeon related factors that may influence PRO's

 

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