Like all medicines, cannabis products can cause side effects. These are common but usually mild and improve quickly if you lower the dose or stop taking the product.
Common side effects include:
- Dry mouth
- Dizziness or light‑headedness
- Stomach rumbling
- Increased appetite
Cannabis does not usually cause constipation.
If you take too much during the day, you may feel sleepy. If this happens, reduce your dose.
Cannabis can cause drowsiness. Do not drive or use heavy machinery right after taking it. Once you know how it affects you, you may be able to drive normally at least 4 hours after a dose, as long as you feel alert and safe to do so.
Cannabis can lower blood pressure and increase heart rate. People with unstable heart conditions should not use cannabis products.
THC can worsen confusion or psychosis in some people. If you have had recent confusion (delirium) or a history of psychosis (such as schizophrenia), a CBD‑only product is recommended if cannabis is considered at all.
Some people who previously used a lot of cannabis have had a condition called cannabis‑induced hyperemesis syndrome, which causes repeated vomiting. If this has happened to you, you should avoid THC entirely.
Cannabis should not be used during pregnancy or breastfeeding, as it can harm the baby. Cannabis can also affect sperm and should be avoided by people trying to conceive.
Cannabis can interact with some medicines, including certain blood thinners. Ask your pharmacist, family doctor or cancer care team to check for interactions before you start, and again if you start any new medication.
Having a substance use disorder should not prevent someone from using medical cannabis during cancer care. Cannabis has been shown to reduce cravings for some substances and, in places where it is legal, has been linked to fewer opioid overdose deaths.
Tolerance and dependence can occur with high doses, however, cannabis misuse disorder (addiction) does not happen when cannabis-based medicine is used in low doses for symptom management.
For some patients, especially those who have both cancer and a substance use disorder, cannabis can make it easier to manage symptoms and stay on cancer treatment. It may work better for pain than opioids like morphine, hydromorphone or oxycodone, particularly if those medicines no longer work well for them.