Distal: Whipple resection with portal lymphadenectomy
Mid-bile duct: Bile duct resection with portal lymphadenectomy. Intraoperative frozen sections should be obtained to assess margins.
Proximal: Right or left hepatectomy (including caudate lobe) with bile duct resection and portal lymphadenectomy.
Note: highly selected patients may be candidates for liver transplantation.
