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Breast

Protocols

Hormonal Therapy

(Neoadjuvant, Adjuvant, Locally Advanced)

BRAJANAS

Neoadjuvant or Adjuvant Therapy for Breast Cancer using Anastrozole in Postmenopausal Women


BRAJEXE

Neoadjuvant or Adjuvant Therapy for Breast Cancer using Exemestane in Postmenopausal Women


BRAJLDTAM

Adjuvant Treatment of Resected Ductal Carcinoma In Situ using Tamoxifen


BRAJLET

Neoadjuvant or Adjuvant Therapy for Breast Cancer using Letrozole in Postmenopausal Women


BRAJLHRHAI

Neoadjuvant or Adjuvant Ovarian Suppression and Aromatase Inhibitor in Premenopausal Women with High Risk Early Stage Breast Cancer


BRAJLHRHT

Neoadjuvant or Adjuvant Therapy for Breast Cancer Using a LHRH Agonist and Tamoxifen


BRAJTAM

Neoadjuvant or Adjuvant Therapy for Breast Cancer Using Tamoxifen


UBRAJABEAI

Treatment of Adjuvant Breast Cancer using Abemaciclib and Aromatase Inhibitor With or Without LHRH Agonist


UBRAJABET

Treatment of Adjuvant Breast Cancer using Abemaciclib and Tamoxifen With or Without LHRH Agonist

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Anti-HER2 Therapy

(Neoadjuvant, Adjuvant, Locally Advanced)

BRAJACTT

Neoadjuvant or Adjuvant Therapy for Breast Cancer using DOXOrubicin and Cyclophosphamide followed by PACLitaxel and Trastuzumab


BRAJACTTG

Neoadjuvant or Adjuvant Therapy for Breast Cancer Using Dose Dense Therapy: DOXOrubicin and Cyclophosphamide Followed by PACLitaxel and Trastuzumab


BRAJDCARBT

Neoadjuvant or Adjuvant Therapy for Breast Cancer Using DOCEtaxel, CARBOplatin, and Trastuzumab


BRAJFECDT

Neoadjuvant or Adjuvant Therapy for Breast Cancer Using Fluorouracil, Epirubicin and Cyclophosphamide Followed by DOCEtaxel and Trastuzumab


BRAJPNCT

Alternative Neoadjuvant or Adjuvant Therapy for Breast Cancer using PACLitaxel NAB (ABRAXANE), CARBOplatin and Trastuzumab


BRAJPNT

Alternative Adjuvant Therapy for Breast Cancer using PACLitaxel NAB (ABRAXANE) and Trastuzumab


BRAJTDC

Neoadjuvant or Adjuvant Therapy for Breast Cancer Using Trastuzumab, DOCEtaxel and Cyclophosphamide


BRAJTR

Adjuvant Therapy for Breast Cancer Using Trastuzumab following the Completion of Chemotherapy (Sequential)


BRAJTTW

Adjuvant Therapy for Breast Cancer Using Weekly PACLitaxel and Trastuzumab


BRLAACDT

Treatment of Locally Advanced Breast Cancer Using DOXOrubicin and Cyclophosphamide Followed by DOCEtaxel and Trastuzumab


UBRAJKAD

Adjuvant Therapy for Breast Cancer using Trastuzumab Emtansine (KADCYLA)

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Chemotherapy

(Neoadjuvant, Adjuvant, Locally Advanced)

BRAJAC

Adjuvant Therapy for Breast Cancer Using DOXOrubicin and Cyclophosphamide


BRAJACT

Neoadjuvant or Adjuvant Therapy for Breast Cancer using DOXOrubicin and Cyclophosphamide followed by PACLitaxel


BRAJACTG

Neoadjuvant or Adjuvant Therapy for Breast Cancer using Dose Dense Therapy: DOXOrubicin and Cyclophosphamide followed by PACLitaxel


BRAJACTW

Neoadjuvant or Adjuvant therapy for Early Breast Cancer Using DOXOrubicin and Cyclophosphamide Followed by Weekly PACLitaxel


BRAJCAP

Therapy of Adjuvant Breast Cancer using Capecitabine


BRAJCMFPO (deleted 01 Sep 2023)

Adjuvant Therapy for High-Risk Breast Cancer using Cyclophosphamide (oral), Methotrexate and Fluorouracil


BRAJDAC

Neoadjuvant or Adjuvant Therapy for Breast Cancer using Cyclophosphamide, DOXOrubicin and DOCEtaxel


BRAJDC

Adjuvant Therapy for Breast Cancer Using DOCEtaxel and Cyclophosphamide


BRAJFEC

Adjuvant Therapy for Breast Cancer Using Fluorouracil, Epirubicin and Cyclophosphamide


BRAJFECD

Neoadjuvant or Adjuvant Therapy for Breast Cancer Using Fluorouracil, Epirubicin, Cyclophosphamide and DOCEtaxel


BRAJPN

Alternative Adjuvant Therapy for Breast Cancer using PACLitaxel NAB (ABRAXANE)


BRLAACD

Treatment of Locally Advanced Breast Cancer Using DOXOrubicin and Cyclophosphamide Followed by DOCEtaxel


BRLACPNAC

Alternative NEOAdjuvant Therapy for Triple Negative Breast Cancer using CARBOplatin and PACLitaxel NAB (ABRAXANE) Followed by DOXOrubicin and Cyclophosphamide


BRLACPNACG

Alternative NEOAdjuvant Therapy for Triple Negative Breast Cancer using Dose Dense Therapy: CARBOplatin and PACLitaxel NAB (ABRAXANE) Followed by DOXOrubicin and Cyclophosphamide


BRLACTWAC

NEOAdjuvant Therapy for Triple Negative Breast Cancer using Carboplatin and Weekly PACLitaxel Followed by DOXOrubicin and Cyclophosphamide


BRLACTWACG

NEOAdjuvant Therapy for Triple Negative Breast Cancer using Dose Dense Therapy: Carboplatin and Weekly PACLitaxel Followed by DOXOrubicin and Cyclophosphamide


BRLAPNAC

Alternative NEOAdjuvant Therapy for Locally Advanced Breast Cancer using PACLitaxel NAB (ABRAXANE) followed by DOXOrubicin and Cyclophosphamide


BRLAPNACG

Alternative NEOAdjuvant Therapy for Breast Cancer using Dose Dense Therapy: PACLitaxel NAB (ABRAXANE) followed by DOXOrubicin and Cyclophosphamide


BRLATACG

NEOAdjuvant Therapy for Breast Cancer Using Dose Dense Therapy: PACLitaxel Followed by DOXOrubicin and Cyclophosphamide


BRLATWAC

NEOAdjuvant Therapy for Locally Advanced Breast Cancer Using Weekly PACLitaxel Followed by DOXOrubicin and Cyclophosphamide


BRPCTAC (see under Immunotherapy Section)

BRPCWTAC (see under Immunotherapy Section)

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Immunotherapy

(Neoadjuvant, Adjuvant, Locally Advanced)

BRAJPEM

Adjuvant Treatment of Resected Triple Negative Breast Cancer using Pembrolizumab


BRPCTAC

NEOAdjuvant Therapy for Triple Negative Breast Cancer using Pembrolizumab with CARBOplatin and Weekly PACLitaxel, Followed by DOXOrubicin and Cyclophosphamide


BRPCWTAC

NEOAdjuvant Therapy for Triple Negative Breast Cancer using Pembrolizumab, Weekly CARBOplatin and Weekly PACLitaxel, Followed by DOXOrubicin and Cyclophosphamide

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Targeted Therapy, Bisphosphonates

(Neoadjuvant, Adjuvant, Locally Advanced)

BRAJPAM

Adjuvant Therapy for Breast Cancer in Post-menopausal Women Using Pamidronate


BRAJZOL2

Adjuvant Therapy for Breast Cancer in Post-Menopausal Women Using 3-Monthly Zoledronic Acid


BRAJZOL5

Adjuvant Therapy for Breast Cancer in post-menopausal Women Using 6-Monthly Zoledronic Acid


UBRAJOLA

Treatment of BRCA-Mutated High-Risk Early Breast Cancer using Olaparib

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Hormonal Therapy

(Advanced)

BRAVANAS

Palliative Therapy for Metastatic Breast Cancer Using Anastrozole


BRAVEVEX

Therapy for Advanced Breast Cancer Using Everolimus and Exemestane


BRAVEXE

Palliative Therapy for Advanced Breast Cancer Using Exemestane


BRAVLET

Palliative Therapy for Advanced Breast Cancer Using Letrozole


BRAVLHRHAI (previously BRAVLHRHA)

Therapy for Advanced Breast Cancer Using a LHRH Agonist and an Aromatase Inhibitor


BRAVLHRHT

Palliative Therapy for Breast Cancer Using a LHRH agonist and tamoxifen


BRAVMEG

Palliative Therapy for Advanced Breast Cancer Using Megestrol


BRAVPALAI

Therapy of Advanced Breast Cancer Using Palbociclib and Aromatase Inhibitor With or Without LHRH Agonist


BRAVPBFLV

Therapy of Advanced Breast Cancer using Palbociclib and Fulvestrant With or Without LHRH Agonist


BRAVRBFLV

Therapy of Advanced Breast Cancer using Ribociclib and Fulvestrant With or Without LHRH Agonist


BRAVRIBAI

Therapy of Advanced Breast Cancer Using Ribociclib and Aromatase Inhibitor With or Without LHRH Agonist


BRAVTAM

Palliative Therapy for Breast Cancer Using Tamoxifen


BRAVTEST

Palliative Therapy for Metastatic Breast Cancer Using Testosterone Enanthate

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Anti-HER2 Therapy

(Advanced)

BRAVENH

Palliative Therapy for Metastatic Breast Cancer using Trastuzumab Deruxtecan (ENHERTU)


BRAVKAD

Palliative Therapy for Metastatic Breast Cancer Using Trastuzumab Emtansine (KADCYLA)


BRAVLCAP

Therapy for Metastatic Breast Cancer Using Capecitabine and Lapatinib


BRAVPTRAD

Palliative Therapy for Metastatic Breast Cancer Using PERTuzumab, Trastuzumab, and DOCEtaxel as First-Line Treatment for Advanced Breast Cancer


BRAVPTRAT

Palliative Therapy for Metastatic Breast Cancer Using PERTuzumab, Trastuzumab, and PACLitaxel as First-Line Treatment for Advanced Breast Cancer


BRAVPTRVIN

Palliative Therapy for Metastatic Breast Cancer using PERTuzumab, Trastuzumab, and Vinorelbine as First-Line Treatment for Advanced Breast Cancer


BRAVTCAP

Palliative Therapy for Metastatic Breast Cancer Using Trastuzumab and Capecitabine


BRAVTR

Palliative Therapy for Metastatic Breast Cancer Using Trastuzumab


UBRAVTTCAP

Palliative Therapy for Metastatic Breast Cancer using Trastuzumab, Tucatinib, and Capecitabine

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Chemotherapy

(Advanced)

BRAVA7

Palliative Therapy for Metastatic Breast Cancer Using Weekly DOXOrubicin


BRAVABR

Palliative Therapy for Metastatic Breast Cancer using PACLitaxel NAB (ABRAXANE)


BRAVAC

Palliative Therapy for Metastatic Breast Cancer Using DOXOrubicin and Cyclophosphamide


BRAVCAP

Therapy for Metastatic Breast Cancer Using Capecitabine


BRAVCMF

Palliative Therapy for Advanced Breast Cancer Using Cyclophosphamide, Methotrexate and Fluorouracil


BRAVCMPO

Palliative Therapy for Metastatic Breast Cancer Using Metronomic Low-Dose Oral Cyclophosphamide and Methotrexate


BRAVDOC

Palliative Therapy for Metastatic Breast Cancer Using DOCEtaxel


BRAVDOC7

Palliative Therapy for Metastatic Breast Cancer Using Weekly Docetaxel


BRAVENH (see under Anti-HER2 section)


BRAVERIB

Palliative Therapy for Metastatic Breast Cancer Using eriBULin


BRAVGEM

Palliative Therapy for Metastatic Breast Cancer Using Gemcitabine


BRAVGEMD

Palliative Therapy for Metastatic Breast Cancer Using Gemcitabine and DOCEtaxel


BRAVGEMP

Palliative Therapy for Metastatic Breast Cancer Using CISplatin and Gemcitabine


BRAVGEMT

Palliative Therapy for Metastatic Breast Cancer Using Gemcitabine and PACLitaxel


BRAVHDMTX

Treatment of Meningeal Disease using High-Dose Methotrexate with Leucovorin Rescue


BRAVNAV

Palliative Therapy for Symptomatic Metastatic Breast Cancer Using Vinorelbine


BRAVPGC (see under Immunotherapy section)

BRAVPP (see under Immunotherapy section)

BRAVPPN (see under Immunotherapy section)


BRAVSG

Palliative Therapy for Metastatic Triple Negative Breast Cancer using Sacituzumab Govitecan


BRAVTAX

Palliative Therapy for Metastatic Breast Cancer Using PACLitaxel


BRAVTW

Palliative Therapy for Metastatic Breast Cancer Using Weekly PACLitaxel (3 Weeks Out of 4 Weeks Schedule)

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Immunotherapy

(Advanced)

BRAVPEM

Treatment of Metastatic Breast Cancer using Pembrolizumab


BRAVPEM6

Treatment of Metastatic Breast Cancer using 6-Weekly Pembrolizumab


BRAVPGC

Palliative Therapy for Metastatic Breast Cancer using Pembrolizumab, Gemcitabine, and CARBOplatin


BRAVPP

Palliative Therapy for Metastatic Breast Cancer using Pembrolizumab with PACLitaxel


BRAVPPN

Palliative Therapy for Metastatic Breast Cancer using Pembrolizumab and PACLitaxel NAB (ABRAXANE)

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Bisphosphonates

(Advanced)

BRAVCLOD

For Therapy of Bone Metastases in Breast Cancer Using Oral Clodronate


BRAVPAM

Prevention of Skeletal Related Events Secondary to Breast Cancer Metastases Using Pamidronate


BRAVZOL

Treatment of Acute Bone Pain Secondary to Breast Cancer Metastases Using IV Zoledronic Acid

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Funding algorithm

The funding algorithm provides information on what anti-cancer systemic therapy treatments are covered on the BC Cancer Benefit Drug List (formulary). It may not be a complete list of all treatment options that may be available and recommended by the treating physician.

Terms of use

The information contained in these documents is a statement of consensus of BC Cancer professionals regarding their views of currently accepted approaches to treatment. Any clinician seeking to apply or consult these documents is expected to use independent medical judgement in the context of individual clinical circumstances to determine any patient's care or treatment. Use of these documents is at your own risk and is subject to BC Cancer's terms of use.

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SOURCE: Breast ( )
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