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Gastrointestinal

Protocols

Resectable Colorectal (Adjuvant)

GIAJCAP

Adjuvant Therapy of Colon Cancer Using Capecitabine


GIAJCAPOX

Adjuvant Combination Chemotherapy for Stage III and Stage IIB Colon Cancer Using Oxaliplatin and Capecitabine


GIAJFFOX

Adjuvant Combination Chemotherapy for Stage III and Stage IIB Colon Cancer Using Oxaliplatin, Fluorouracil and Leucovorin


GIAJFL

Adjuvant Therapy of Colon Cancer Using Fluorouracil Injection and Infusion and Leucovorin Infusion


GIAJRALOX

Adjuvant Combination Chemotherapy for Node Positive Colon Cancer Using Oxaliplatin and Raltitrexed in Patients Intolerant to Fluorouracil or Capecitabine


GIRAJCOX

Adjuvant Combination Chemotherapy for Stage III Rectal Cancer Using Oxaliplatin and Capecitabine


GIRAJFFOX

Adjuvant Combination Chemotherapy for Stage III Rectal Cancer Using Oxaliplatin, Fluorouracil and Leucovorin


GIRCAP

Adjuvant Therapy for Stage II and III Rectal Cancer Previously Treated with Preoperative Radiation Therapy using Capecitabine


GIRCRT

Combined Modality Adjuvant Therapy for High Risk Rectal Carcinoma Using Capecitabine and Radiation Therapy


GIRINFRT

Combined Modality Adjuvant Therapy for High Risk Rectal Carcinoma Using Capecitabine, Infusional Fluorouracil and Radiation Therapy


Unresectable Colorectal (Advanced)

GIAVCAP

Palliative Therapy of Advanced Colorectal Cancer using Capecitabine


GIAVCAPB

Palliative Therapy of Advanced Colorectal Cancer using Capecitabine and Bevacizumab


GIAVCETIR

Third Line Treatment of Metastatic Colorectal Cancer Using Cetuximab in Combination with Irinotecan


GIAVCRT

Combined Modality Therapy for Metastatic Rectal Carcinoma using Capecitabine and Radiation Therapy

GIAVFL

Palliative Combination Chemotherapy for Metastatic Colorectal Cancer Using Fluorouracil Injection and Infusion and Leucovorin Infusion


UGIAVPANEN

Treatment of BRAF V600E - Mutated Metastatic Colorectal Cancer using PANitumumab and Encorafenib


GIAVPANI

Palliative Third Line Treatment of Metastatic Colorectal Cancer Using Panitumumab


UGIAVPEM

First-Line Treatment of dMMR/MSI-H Metastatic Colorectal Cancer using Pembrolizumab


UGIAVPEM6

First-Line Treatment of dMMR/MSI-H Metastatic Colorectal Cancer using 6-Weekly Pembrolizumab


GIAVRALIR

Palliative Therapy of Metastatic Colorectal Cancer using Irinotecan and Raltitrexed in Patients Intolerant to Fluorouracil or Capecitabine


GIAVRALOX

Palliative Therapy of Metastatic Colorectal Cancer using Oxaliplatin and Raltitrexed in Patients Intolerant to Fluorouracil or Capecitabine


GICAPIRI

Palliative Combination Chemotherapy for Metastatic Colorectal Cancer Using Irinotecan and Capecitabine in Patients Unsuitable for GIFOLFIRI


GICAPOX

Palliative Combination Chemotherapy for Metastatic Colorectal Cancer Using Oxaliplatin and Capecitabine


GICIRB

Palliative Combination Chemotherapy for Metastatic Colorectal Cancer Using Irinotecan, Bevacizumab and Capecitabine


GICOXB

Palliative Combination Chemotherapy for Metastatic Colorectal Cancer Using Oxaliplatin, Bevacizumab and Capecitabine


GIFFIRB

Palliative Combination Chemotherapy for Metastatic Colorectal Cancer Using Irinotecan, Fluorouracil, Leucovorin and Bevacizumab


GIFFIRPAN

Palliative Combination Chemotherapy for Metastatic Colorectal Cancer Using Irinotecan, Fluorouracil, Leucovorin, and PANitumumab


GIFFOXB

Palliative Combination Chemotherapy for Metastatic Colorectal Cancer Using Oxaliplatin, Fluorouracil, Leucovorin and Bevacizumab


GIFFOXPAN

Palliative Combination Chemotherapy for Metastatic Colorectal Cancer Using Oxaliplatin, Fluorouracil, Leucovorin, and PANitumumab


GIFOLFIRI

Palliative Combination Chemotherapy for Metastatic Colorectal Cancer Using Irinotecan, Fluorouracil and Leucovorin


GIFOLFOX

Palliative Combination Chemotherapy for Metastatic Colorectal Cancer Using Oxaliplatin, Fluorouracil and Leucovorin


GIIR

Palliative Chemotherapy of Metastatic Colorectal Cancer Using Irinotecan


GIIRINALT

Palliative Chemotherapy of Metastatic Colorectal Cancer Using Weekly Irinotecan


GIRALT

Palliative Chemotherapy for Metastatic Colorectal Cancer using Raltitrexed in Patients with Previous Fluorouracil Toxicity

Esophagus, Stomach

GIAJNIV

Adjuvant Treatment of Resected Esophageal or Gastroesophageal Junction Cancer using Nivolumab


GIAVDOC

Palliative Treatment of Metastatic Esophagogastric Adenocarcinoma with DOCEtaxel


GIEFFOXRT

Combined Modality Therapy for Locally Advanced Esophageal Cancer using Oxaliplatin, Fluorouracil, Leucovorin, and Radiation Therapy


GIENACTRT

Neoadjuvant Treatment of Esophageal and Gastroesophageal Carcinomas Using CARBOplatin, PACLitaxel and Radiation Therapy


GIFUC

Palliative Chemotherapy for Upper Gastrointestinal Tract Cancer (Gastric, Esophageal, Gall Bladder Carcinoma and Cholangiocarcinoma) and Metastatic Anal Cancer Using Infusional Fluorouracil and CISplatin


GIGAJCOX

Adjuvant Chemotherapy in Gastric Cancer Patients with D2 Resection (Node Negative) or Ineligible for Adjuvant Chemoradiation Using Oxaliplatin and Capecitabine


GIGAJCPRT

Adjuvant Chemotherapy of Gastric Cancer Patients with Completely Resected Gastric Cancer Using CISplatin and Capecitabine and Radiation Therapy


GIGAJFFOX

Adjuvant Chemotherapy of Gastric Cancer Patients with D2 Resection (Node Negative) or Ineligible for Adjuvant Chemoradiation Using Oxaliplatin, Fluorouracil, and Leucovorin


GIGAVCCT

Palliative Treatment of Metastatic or Locally Advanced Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma Using CISplatin, Capecitabine and Trastuzumab


GIGAVCFT

Palliative Treatment of Metastatic or Inoperable, Locally Advanced Gastric or Gastroesophageal Junction Adenocarcinoma using CISplatin, Infusional Fluorouracil and Trastuzumab


GIGAVCOX

Advanced Gastric, Gastroesophageal Junction or Esophageal Carcinoma using Capecitabine and Oxaliplatin

GIGAVCOXN

First-Line Treatment of Locally Advanced or Metastatic Esophageal, Gastroesophageal, or Gastric Cancer using Oxaliplatin, Capecitabine and Nivolumab

GIGAVCOXP

First-Line Treatment of Locally Advanced or Metastatic Gastroesophageal Cancer using Oxaliplatin, Capecitabine and Pembrolizumab

GIGAVCOXT

Palliative Treatment of Metastatic or Locally Advanced Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma Using Capecitabine, Oxaliplatin, and Trastuzumab 

GIGAVFFOX

Palliative Treatment of Metastatic or Locally Advanced Gastric, Gastroesophageal Junction or Esophageal Carcinoma using Oxaliplatin, Fluorouracil and Leucovorin

GIGAVFFOXN

First-Line Treatment of Locally Advanced or Metastatic Esophageal, Gastroesophageal, or Gastric Cancer using Oxaliplatin, Fluorouracil, Leucovorin and Nivolumab

GIGAVFFOXP

First-Line Treatment of Locally Advanced or Metastatic Gastroesophageal Cancer using Oxaliplatin, Fluorouracil, Leucovorin and Pembrolizumab


GIGAVFFOXT

Palliative Treatment of Metastatic or Locally Advanced HER-2 Positive Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma Using Oxaliplatin, Fluorouracil, Leucovorin, and Trastuzumab


GIGAVRAMT

Second-Line Therapy for Metastatic or Locally Advanced Gastric or Gastroesophageal Junction Cancer Using Weekly PACLitaxel and Ramucirumab


GIGAVTR

Continuation of Palliative Treatment of Metastatic or Inoperable, Locally Advanced Gastric or Gastroesophageal Junction Adenocarcinoma using Trastuzumab


GIGAVTRFT

Third-Line Therapy of Advanced Gastroesophageal Carcinoma Using Trifluridine-Tipiracil


GIGECC

Perioperative Treatment of Resectable Adenocarcinoma of the Stomach, Gastroesophageal Junction or Lower 1/3 Esophagus Using Epirubicin, CISplatin and Capecitabine


GIGFLODOC

Perioperative Treatment of Resectable Adenocarcinoma of the Stomach, Gastroesophageal Junction or Lower 1/3 Esophagus using DOCEtaxel, Oxaliplatin, Infusional Fluorouracil, and Leucovorin


GIGFOLFIRI

Second Line Palliative Combination Chemotherapy for Metastatic Gastric or Esophageal Adenocarcinoma Using Irinotecan, Fluorouracil and Leucovorin

Pancreas, Gall Bladder, Biliary Tract

GIAVDUR4

Treatment of Advanced Biliary Tract Cancer using Durvalumab


GIAVDURPG

First-line Palliative Treatment of Advanced Biliary Tract Cancer using Durvalumab, Gemcitabine and Platinum


GIAVPG

First-line Palliative Chemotherapy for Advanced Gallbladder, Pancreatic Carcinoma, and Cholangiocarcinoma using Gemcitabine and CISplatin


GIBAJCAP

Adjuvant Therapy of Biliary Cancer using Capecitabine


GIBYTT

Yttrium-90 for Transarterial Radioembolization (TARE) for Locally Advanced Cholangiocarcinoma or Gallbladder Carcinoma Not Amenable for Surgical Resection


GIFIRINOX

Palliative Combination Chemotherapy for Advanced Pancreatic Adenocarcinoma Using Irinotecan, Oxaliplatin, Fluorouracil and Leucovorin


GIFUC

(See under Esophagus, Stomach Section)


GIPAJFIROX

Adjuvant Chemotherapy for Resected Pancreatic Adenocarcinoma Using Irinotecan, Oxaliplatin, Fluorouracil and Leucovorin


GIPAJGCAP

Adjuvant Chemotherapy for Resected Pancreatic Adenocarcinoma Using Capecitabine and Gemcitabine


GIPAJGEM

Adjuvant Chemotherapy for Pancreatic Adenocarcinoma Using Gemcitabine


GIPAVCAP (deleted 01 Jul 2024)

Second line Treatment of Metastatic or Unresectable Pancreatic Adenocarcinoma Using Capecitabine

ONLY use GIPAVCAP to complete treatment with existing patients. Use GIAVCAP for new patients

GIPAVFFIRI

Second Line Treatment for Metastatic Pancreatic Cancer Using Irinotecan, Fluorouracil and Leucovorin


GIPAVFFOX

Palliative Combination Chemotherapy for Metastatic Pancreatic Cancer Using Oxaliplatin, Fluorouracil, and Leucovorin


GIPGEM

Palliative Therapy for Pancreatic Adenocarcinoma, Gallbladder Cancer, and Cholangiocarcinoma Using Gemcitabine


GIPGEMABR

First Line Treatment of Locally Advanced and Metastatic Pancreatic Cancer with PACLitaxel NAB (ABRAXANE) and Gemcitabine

Liver

GIA

Palliative Therapy for Hepatoma Using DOXOrubicin


GIATZB

First-Line Treatment of Advanced Hepatocellular Carcinoma using Atezolizumab and Bevacizumab


UGICABO

Treatment of Advanced Hepatocellular Carcinoma using Cabozantinib


GIDEBTACE

Transarterial Chemoembolization (TACE) of Hepatocellular Carcinoma Using Drug-Eluting Bead (DEB) Loaded with DOXOrubicin


GILEN

First Line Therapy of Advanced Hepatocellular Carcinoma Using Lenvatinib


GIREGO

Treatment of Advanced Hepatocellular Carcinoma Using Regorafenib


GISORAF

Therapy for Advanced Hepatocellular Carcinoma Using SORAfenib


GITREMDUR

First-Line Treatment of Advanced Hepatocellular Carcinoma using Tremelimumab and Durvalumab


UGIYTT

Yttrium-90 for Transarterial Radioembolization (TARE) for Hepatocellular Cancer or Neuroendocrine Tumours with Hepatic Disease

Carcinoid & Neuroendocrine Tumours

GIAVTZCAP

Palliative Therapy of Metastatic Neuroendocrine Cancer Using Temozolomide and Capecitabine


GIENDO2

Palliative Therapy for Pancreatic Endocrine Tumours Using Streptozocin and DOXOrubicin


UGILAN

Symptomatic Management of Functional Carcinoid and Neuroendocrine Tumours of the GI Tract Using Lanreotide (SOMATULINE AUTOGEL®)

UGINETEV

Treatment of Advanced Neuroendocrine Tumours of Gastrointestinal Origin (Non-Functional) Using Everolimus

GINFOCLAR

Management of Non-Functional Neuroendocrine Tumours of the GI Tract Using Octreotide (SANDOSTATIN LAR)

GINPRRT

Out-of-Province Peptide Receptor Radionuclide Therapy for Advanced Neuroendocrine Tumours


GIOCTLAR

Symptomatic Management of Functional Carcinoid and Neuroendocrine Tumours of the GI Tract Using Octreotide


GIPE

Palliative Therapy of Neuroendocrine Tumours Using CISplatin and Etoposide


GIPNEVER

Palliative Treatment of Advanced Pancreatic Neuroendocrine Tumours using Everolimus


GIPNSUNI

Palliative Treatment of Advanced Pancreatic Neuroendocrine Tumours Using SUNItinib


UGIPRRT

Peptide Receptor Radionuclide Therapy (PRRT) using Lutetium 177Lu-Dotatate (LUTATHERA) for Treatment in Patients with Somatostatin Receptor Positive Neuroendocrine Tumours

Others

GIAAVCT

First-Line Palliative Treatment of Metastatic Anal Squamous Cell Carcinoma Using CARBOplatin and Weekly PACLitaxel

GICART

Combined Modality Therapy for Carcinoma of the Anal Canal Using Mitomycin, Capecitabine and Radiation Therapy

GICPART

Combined Modality Therapy for Carcinoma of the Anal Canal Using CISplatin, Capecitabine and Radiation Therapy

GIFUART

Combined Modality Curative Therapy for Carcinoma of the Anal Canal Using Mitomycin, Fluorouracil and Radiation Therapy

GIFUPART

Combined Modality Curative Therapy for Carcinoma of the Anal Canal Using CISplatin, Infusional Fluorouracil and Radiation Therapy

GIFUC

(SEE UNDER ESOPHAGUS, STOMACH SECTION)

GIFUIP

Chemotherapy of Pseudomyxoma Peritonei Using Intraperitoneal Mitomycin and Fluorouracil

GIGAVCC

Palliative Therapy of Metastatic or Locally Advanced Anal Squamous Cell Carcinoma using CISplatin and Capecitabine

GIHIPEC

Hyperthermic Intraperitoneal Chemotherapy (HIPEC) for Patients with Peritoneal Carcinomatosis from Limited Advanced Colorectal and Appendiceal Carcinomas Using Oxaliplatin and Fluorouracil (5-FU)

GIPMHIPEC

Hyperthermic Intraperitoneal Chemotherapy (HIPEC) for Patients with Peritoneal Mesothelioma Using Doxorubicin, Cisplatin and Paclitaxel
Funding algorithm

The funding algorithm provides information on what anti-cancer systemic therapy treatments are covered on the BC Cancer Benefit Drug List (formulary). It may not be a complete list of all treatment options that may be available and recommended by the treating physician.

Terms of use

The information contained in these documents is a statement of consensus of BC Cancer professionals regarding their views of currently accepted approaches to treatment. Any clinician seeking to apply or consult these documents is expected to use independent medical judgement in the context of individual clinical circumstances to determine any patient's care or treatment. Use of these documents is at your own risk and is subject to BC Cancer's Terms of Use.

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