Added 06 March 2013
- Primary tumour site- cervical esophagus, mid-esophagus, distal esophagus, esophago-gastric junction (EGJ). [Adenocarcinoma arising at the EGJ or within the proximal 5cm of the stomach and involving the EGJ are staged as an esophageal tumour ]
- Histologic type
- Histologic grade (well, moderately, poorly differentiated or undifferentiated)
- Size (Longitudinal tumour dimension, semi-circumferential/ circumferential lesion)
- Microscopic tumour extension/invasion
- Lymph-Vascular invasion (present/absent)
- Surgical margins: proximal, distal, omental (radial), deep (for endoscopic resections); state if involved by dysplasia or invasive carcinoma; state closest approach of invasive carcinoma to margin in mm.)
- Treatment effect(post neo-adjuvant therapy, if applicable) (present/absent)
- Status of background mucosa (i.e. Barrett’s esophagus, dysplasia, etc.)
- Lymph node status (x of y lymph nodes positive)
- HER2-neu testing in gastroesophageal adenocarcinoma:
- by immunohistochemistry (IHC)
- fluorescence in-situ hybridization if IHC is 2+
- pTNM tumour stage (AJCC 7th edition)
Primary Tumour (pT) (Note: this is optional)
pTX: Cannot be assessed
pT0: No evidence of primary tumour
pTis: High-grade dysplasia
pT1: Tumour invades lamina propria, muscularis mucosae, or submucosa
pT1a: Tumour invades lamina propria or muscularis mucosae
pT1b: Tumour invades submucosa
pT2: Tumour invades muscularis propria
pT3: Tumour invades adventitia
pT4: Tumour invades adjacent structures (specify): ______________________
pT4a: Resectable tumour invading pleura, pericardium, or diaphragm
pT4b: Unresectable tumour invading other adjacent structures, such as aorta, vertebral body, trachea, etc
Regional Lymph Nodes (pN)
pNX: Cannot be assessed
pN0: No regional lymph node metastasis
pN1: Regional lymph node metastasis involving 1 to 2 nodes
pN2: 3 to 6 nodes involved
pN3: 7 or more nodes involved
Distant Metastasis (pM)
Not applicable
pM1: Distant metastasis (specify site(s))
