Updated 15 February 2006
Involvement of the skin by any of the usual malignant lymphomas should be treated as appropriate for the type and stage of disease and age of the patient. The specific management of the T-cell cutaneous lymphomas, mycoses fungoides and Sézary syndrome, is described in the separate section of the Cancer Management Manual entitled Skin Lymphomas.
The specific entity primary cutaneous anaplastic large cell lymphoma (cutaneous ALCL) sits at the interface between systemic ALCL and the benign condition lymphomatoid papulosis. Cutaneous ALCL has a natural history that is distinct from systemic ALCL. After reviewing our experience with cutaneous ALCL the BCCA Lymphoma Tumor Group could not find convincing evidence that chemotherapy contributes to disease control when included in primary management. Thus, the group recommends local complete resection if feasible followed by local irradiation but does not recommend the routine inclusion of chemotherapy.